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"We cannot tolerate an EPA administrator who treats our families as expendable."
Hundreds of health experts are demanding the removal of Environmental Protection Agency Administrator Lee Zeldin over his gutting of key regulations that they say will endanger Americans' livelihoods.
A letter released Thursday by Climate Action Campaign outlines Zeldin's threats to public health and explains why he should not be serving as the top US environmental regulator.
"Administrator Zeldin is pursuing a deregulatory agenda that will result in a massive increase in health-damaging air pollution, toxic chemicals, and climate-heating greenhouse gases," says the letter, which is signed by nearly 300 medical experts, including physicians, nurses, and public health researchers.
"And just last month, the administration laid bare its decision to no longer count the economic value of health benefits when setting Clean Air Act rules," the letter adds, "refusing to acknowledge the value of lives saved, hospital visits avoided, and lost work and school days prevented."
The letter also points to the EPA's February decision to revoke the so-called "endangerment finding," which gave the agency authority to regulate greenhouse gases as threats to public health.
Repealing this finding, the letter contends, "will increase the frequency and severity of climate disasters."
According to a Wednesday report from The Associated Press, Zeldin celebrated the EPA's revocation of the finding while delivering a keynote address at the Heartland Institute, a right-wing think tank that has long pushed climate denialism.
"Today is a moment to celebrate," Zeldin said at the event. "It is a day to celebrate vindication."
Margie Alt, director of the Climate Action Campaign, said her group decided to organize the letter among medical experts because "Lee Zeldin is too dangerous to ignore."
"When health experts—the people who see the effects of pollution on their patients every single day—say enough is enough, the rest of us need to pay attention," said Alt. "Zeldin is not just failing Americans. He is actively endangering us. We cannot tolerate an EPA administrator who treats our families as expendable."
This is the second "Game Over Zeldin" letter, following another from over 160 advocacy groups, including Climate Action Campaign and Moms Clean Air Force, last month.
"The wreckage of Lee Zeldin's EPA will be measured in lives lost, jobs destroyed, the costs of illnesses that could have been prevented, and communities devastated."
A month after President Donald Trump and Environmental Protection Agency Administrator Lee Zeldin announced what they celebrated as the "single largest deregulatory action in US history," a coalition of over 160 civil rights, environmental, faith, health, and labor groups came together Tuesday to call for the EPA chief's ouster.
Zeldin was confirmed by Senate Republicans and a trio of Democrats just over a week after Trump returned to power in January 2025. The "Game Over Zeldin" coalition, led by the Climate Action Campaign (CAC) and Moms Clean Air Force, argued in an open letter that no other EPA administrator "in history—Democratic or Republican—has so brazenly betrayed the agency's core mission" to "protect human health and the environment."
"Zeldin has dismantled protections that keep our kids, families, and climate safe, and our air and water clean," the letter notes. "He slashed vital funding, gutted agency staff, and has rigged the system to put corporate polluters first, at the expense of our health. Zeldin's EPA has rejected science and health data—and is refusing to count the value of human lives and health—in order to erode commonsense public health safeguards. He has decimated environmental justice programs and hard-fought progress—entirely eliminating the Office of Environmental Justice and External Civil Rights."
Dominique Browning, director and co-founder of Moms Clean Air Force, pointed out in a Tuesday statement that "in just the past few months, he has supported the Trump administration in using taxpayer money to prop up the coal industry; he has made it easier for polluters to spew mercury—a potent neurotoxin that damages the developing brains of babies—into our air and waterways; and he has rolled back the endangerment finding in an attempt to sabotage EPA's ability to cut climate pollution."
The 2009 endangerment finding underpins all federal climate policy. David Arkush of the watchdog Public Citizen—which is also part of the diverse coalition behind the new letter—warned at the time that if allowed to stand, the repeal "will hamstring the government's ability to combat the most terrible environmental threat in human history, harming Americans and the world for decades to come."
Young Americans and a coalition of environmental and public health organizations swiftly filed a pair of lawsuits over the rollback. Another group of 24 states, joined by various US cities and counties, sued last week. The most recent filing is expected to be consolidated with the first coalition's case, according to The New York Times, "making for one of the largest legal challenges to date against the Trump administration's unraveling of federal climate policy."
The new letter stresses the consequences of that unraveling, stating that "because of Zeldin's directives, we will suffer more health-damaging air pollution and be exposed to more toxic chemicals in our homes, in our food, in our products, and in our water. Zeldin's rollbacks will lead to more carbon dioxide and methane pollution that will contribute to worsening climate disasters."
"Families across the country, whether rural or urban, are already struggling with the consequences of Zeldin's actions," the letter adds. "The damage he is doing will span generations. Zeldin is deepening environmental injustices and will leave a terrible legacy for our children and grandchildren."
We refuse to stay silent while Lee Zeldin treats our lives like a line item to be deleted. The EPA is for the people, not polluters. His time is up; Lee Zeldin must go. #GameOverZeldin www.gameoverzeldin.com
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— Physicians for Social Responsibility - National (@psr.org) March 24, 2026 at 12:12 PM
CAC director Margie Alt declared Tuesday that "the wreckage of Lee Zeldin's EPA will be measured in lives lost, jobs destroyed, the costs of illnesses that could have been prevented, and communities devastated. We will be paying the price for decades to come."
"Zeldin ignored science as well as the legal and moral precedent," she said. "Instead, he looked at the numbers and made a choice: He decided that corporate bottom lines matter more than our lives. He decided you and your family are expendable. After a year on the job, it is clear that Zeldin is either unable or unwilling to uphold his oath of office or the EPA's fundamental mission. So let us be clear: Our lives are not expendable. Our health is not expendable. Our climate is not expendable. Lee Zeldin must go."
Other organizations that signed on to the letter include Beyond Plastics, Cherokee Concerned Citizens, Clean Air Council, Clean Water Action, Climate Hawks Vote, Earthjustice, Environmental Working Group, Environmental Protection Network, GreenLatinos, Indivisible Action Coalition, Physicians for Social Responsibility, Service Employees International Union, Sierra Club, Union of Concerned Scientists (UCS), and more.
"Administrator Zeldin's established pattern of placing polluter profits above the health and safety of people across the country cannot stand," said UCS president and CEO Gretchen Goldman. "The science establishing harm to human health and the environment from global warming emissions is undeniable. The unprecedented, climate-fueled heatwave a large swath of the United States has been experiencing is only the latest example."
"The public deserves an EPA administrator who will face the challenge of the climate crisis and fossil fuel and toxics pollution head on with proven policy solutions," she argued, "not actively serve as an agent of destruction beholden to the whims of oil, gas, and chemical industry executives and an authoritarian, anti-science US president."
"2025 was full of stark reminders of the urgent need to cut climate pollution, invest in clean energy, and tackle the climate crisis now."
Climate change driven by human burning of fossil fuels helped make 2025 one of the hottest years ever recorded, a scientific report published Monday affirmed, prompting renewed calls for urgent action to combat the worsening planetary emergency.
Researchers at World Weather Attribution (WWA) found that "although 2025 was slightly cooler than 2024 globally, it was still far hotter than almost any other year on record," with only two other recent years recording a higher average worldwide temperature.
For the first time, the three-year running average will end the year above the 1.5°C warming goal, relative to preindustrial levels, established a decade ago under the landmark Paris climate agreement.
"Global temperatures remained very high and significant harm from human-induced climate change is very real," the report continues. "It is not a future threat, but a present-day reality."
"Across the 22 extreme events we analyzed in depth, heatwaves, floods, storms, droughts, and wildfires claimed lives, destroyed communities, and wiped out crops," the researchers wrote. "Together, these events paint a stark picture of the escalating risks we face in a warming world."
The WWA researchers' findings tracked with the findings of United Nations experts and others that 2025 would be the third-hottest year on record.
According to the WWA study:
This year highlighted again, in stark terms, how unfairly the consequences of human-induced climate change are distributed, consistently hitting those who are already marginalized within their societies the hardest. But the inequity goes deeper: The scientific evidence base itself is uneven. Many of our studies in 2025 focused on heavy rainfall events in the Global South, and time and again we found that gaps in observational data and the reliance on climate models developed primarily for the Global North prevented us from drawing confident conclusions. This unequal foundation in climate science mirrors the broader injustices of the climate crisis.
The events of 2025 make it clear that while we urgently need to transition away from fossil fuels, we also must invest in adaptation measures. Many deaths and other impacts could be prevented with timely action. But events like Hurricane Melissa highlight the limits of preparedness and adaptation: When an intense storm strikes small islands such as Jamaica and other Caribbean nations, even relatively high levels of preparedness cannot prevent extreme losses and damage. This underscores that adaptation alone is not enough; rapid emission reductions remain essential to avoid the worst impacts of climate change.
“If we don’t stop burning fossil fuels very, very, quickly, very soon, it will be very hard to keep that goal” of 1.5°C, WWA co-founder Friederike Otto—who is also an Imperial College London climate scientist—told the Associated Press. “The science is increasingly clear.”
The WWA study's publication comes a month after this year's United Nations Climate Change Conference—or COP30—ended in Brazil with little meaningful progress toward a transition from fossil fuels.
Responding to the new study, Climate Action Campaign director Margie Alt said in a statement that "2025 was full of stark reminders of the urgent need to cut climate pollution, invest in clean energy, and tackle the climate crisis now."
"Today’s report is a wake-up call," Alt continued. "Unfortunately, [US President Donald] Trump and Republicans controlling Congress spent the past year making climate denial official US policy and undermining progress to stave off the worst of the climate crisis. Their reckless polluters-first agenda rolled back critical climate protections and attacked and undermined the very agencies responsible for helping Americans prepare for and recover from increasingly dangerous disasters."
"Across the country, people are standing up and demanding their leaders do better to protect our families from climate change and extreme weather," Alt added. "It's time those in power started listening.”