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Protest Against Michigan Data Center

Michigan residents rally against the planned $7 billion Stargate data center in Saline on December 1, 2025.

(Photo by Jim West/UCG/Universal Images Group via Getty Images)

Research Warns of Surge in Cancer-Causing Forever Chemicals From AI Data Center Build-Out

"This global trend towards expanding PFAS production raises the frightening prospect that the partial restrictions on PFAS favored by some politicians will be swept aside by a tidal wave of new output."

As a United Nations expert reiterated a call for a global ban on nonessential uses of per- and polyfluoroalkyl substances, a Swedish nonprofit on Monday released research on how rapidly advancing artificial intelligence and related data centers are helping to drive a surge in PFAS production.

Often called "forever chemicals" because they don't easily break down in human bodies or the environment, PFAS are tied to range of health issues, including various cancers. For months, advocacy groups, journalists, and researchers have stressed that "data centers have a PFAS problem."

That's illustrated clearly in the new report from the International Chemical Secretariat, or ChemSec, which found that an ongoing expansion by many of the world's top 10 PFAS producers "is driven by three main sources of demand—AI and data center infrastructure, semiconductor manufacturing, and lithium-ion battery materials."

Covering the report, The Guardian explained that "PFAS are used for a new form of data center cooling touted as more water- and energy-efficient. In 'two-phase immersion cooling' systems, servers are immersed in a pool of PFAS with a low boiling point. As the hardware gets hot, the fluid boils, drawing heat away as vapor. That rises to a water-cooled condensing coil at the top of the tank, cools back to a liquid state, and reenters the cycle."

ChemSec highlighted that "PFAS manufacturers all over the world are explicitly framing their investments around 'the AI revolution' and microchip fabrication. Battery-grade fluoropolymers are a parallel growth area, in which Arkema and Syensqo are expanding their existing production and building new manufacturing facilities."

In addition to those companies—based in France and Belgium, respectively—the report examines AGC and Daikin in Japan, Archroma in Switzerland, BASF and Bayer in Germany, Chemours and Solstice in the United States, and Orbia Fluor & Energy Materials in Mexico. It also mentions US-based 3M, which "pioneered PFAS production when the chemicals were first invented back in the 1940s" and has plans to leave the industry, though that exit "is still very recent and shrouded in secrecy."

The report points out that "the CEO of US manufacturer Solstice told investors in June that strong AI demand represents a 'generational opportunity' for growth. And we know what that means: a lot more PFAS. Japanese multinational Daikin plans to more than triple its fluoropolymer production capacity in response to the rapidly growing semiconductor market. It is building a new factory, set to start manufacturing more PFAS next year."

"This global trend towards expanding PFAS production raises the frightening prospect that the partial restrictions on PFAS favored by some politicians will be swept aside by a tidal wave of new output," ChemSec warned. "It confirms that the only effective method to end this toxic pollution crisis is to implement universal bans with strictly time-limited derogations to enable certain sectors to adjust."

"The only clear exceptions are 3M and BASF, which have announced they will cease production as expensive legal challenges to their PFAS pollution pile up, and Archroma, which markets PFAS-free alternatives," the group noted. "These companies are sending a signal to the rest of the industry—it can be done, and it must be done."

Bethanie Carney Almroth, an environmental scientist and researcher who became the United Nations' special rapporteur on toxics and human rights last month, spotlighted a recent UN report on PFAS—which urged a ban on nonessential uses—and emphasized that "this is an issue of global environmental justice."

Melanie Benesh, the US-based Environmental Working Group's vice president for government affairs, said in a Monday statement that "PFAS have been linked to kidney, liver, pancreatic, and testicular cancers; as well as immune system suppression, thyroid disease, reduced vaccine efficacy, reproductive and developmental harm, low birth weight, increased cholesterol, weight gain in children and dieting adults, and a growing list of serious health effects."

"For decades, US regulators have let industry set the pace on PFAS. Communities pay the price, like in North Carolina, where Emily Donovan's group Clean Cape Fear is leading the fight to make polluters pay," she continued. "The United States helped create this crisis. It has a responsibility to help end it."

"The world's governments now have a UN report telling them exactly what needs to happen," she added. "The only question left is whether they'll act on it. We must stop making the problem worse and ensure that polluters—not contaminated communities—pay for the damage."

Separately—and on the heels of various artificial intelligence experts sounding the alarm about the pace at which the technology is advancing—UN High Commissioner for Human Rights Volker Türk argued Monday in an open letter that "to protect human rights now and into the future, we must govern AI urgently."

In the United States, the current administration and Republican-controlled Congress have resisted restricting AI, data center construction, or PFAS. Amid mounting calls for limits on the first of those, President Donald Trump claimed on Monday that "the only control or 'guardrails' that AI needs is a STRONG AND SMART (High IQ!) PRESIDENT, and the USA has that, in spades!"

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