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vaccines
Global Health Advocates Call for Massive Mpox Vaccination Effort
"Every necessary step must be taken to get mpox vaccines to the adults and children who need them now," said an epidemiological coordinator for Doctors Without Borders.
Aug 16, 2024
The international medical charity Doctors Without Borders on Friday appealed to wealthy countries that have stockpiles of mpox vaccines to immediately donate doses to several countries in Africa that have been affected by recent outbreaks, as global officials warned the spread of the disease is now a public health emergency of international concern.
The group, also known by its French name, Médecins Sans Frontières (MSF), expressed support for the World Health Organization's (WHO) call for donor countries to help fund a coordinated response to the outbreak, including surveillance, building laboratory capacity, increasing community engagement, and guaranteeing access to treatments, vaccines, and testing.
The current outbreak has been reported mainly in the Democratic Republic of Congo (DRC), where the number of mpox cases this year has surpassed 15,600. More than 530 people have died of the disease this year.
Mpox has been reported in DRC for more than a decade, but with far fewer annual case numbers. More than 100 cases have also been confirmed in the past month in four neighboring countries which have not reported cases of the disease before: Burundi, Kenya, Rwanda, and Uganda.
Dr. Jean Kaseya, director-general of the Africa Centers for Disease Control and Prevention, estimated this week that at least 10 million doses of mpox vaccines will be needed to respond to the growing outbreak.
"We need to have vaccines," Kaseya told NPR. "Today, we are just talking about almost 200,000 doses [becoming] available. We need at least 10 million doses. The vaccine is so expensive—we can put it around $100 per dose. There are not so many countries in Africa that can afford the cost of this vaccine."
Without improved access to vaccines, said Justin Eyong, an intersectional epidemiological coordinator for MSF in DRC, "thousands of people—including children under 15 years old who are particularly affected by mpox (representing 56% and 79% of all cases and deaths from mpox in 2024, respectively)—may be left unprotected."
The U.S. Food and Drug Administration and European Medicines Agency have both approved the MVA-BN vaccine for mpox, which can cause a rash that can be painful and initially look like blisters, as well as fever, chills, and other symptoms.
"Mpox, originating in Africa, was neglected there, and later caused a global outbreak in 2022. It is time to act decisively to prevent history from repeating itself."
With the current price of the MVA-BN vaccine placing it out of reach for most low- and middle-income countries where mpox is endemic or is now spreading, MSF called on its manufacturer, Bavarian Nordic, to partner with African companies "for a full and timely tech transfer" that would allow a vaccine to be produced in Africa.
"With the mpox outbreak in DRC continuing to evolve rapidly, the situation is urgent," Eyong said. "Every necessary step must be taken to get mpox vaccines to the adults and children who need them now."
The current outbreak of mpox is being driven by one of the two genetic clades, or groupings, that characterize the disease. Clade II was behind an outbreak that was declared a global health emergency from 2022-23, but the current spread of the virus is being driven by clade I, which causes more severe disease.
Dimie Ogoina, chair of the International Health Regulations Emergency Committee said Wednesday that the upsurge in cases is "an emergency, not only for Africa, but for the entire globe."
"Mpox, originating in Africa, was neglected there, and later caused a global outbreak in 2022," said Ogoina. "It is time to act decisively to prevent history from repeating itself."
Ogoina's comments were echoed by Ayoade Alakija, chair of the Africa Vaccine Delivery Alliance, who told The Guardian that if European countries were experiencing the current outbreak instead of African nations, "mpox would have already been considered a major international health emergency."
The declaration of an emergency "of international concern," said Alakija, "should focus minds and loosen purse strings so that the response recovers from a sluggish start."
Instead of confronting the threat of a potential new outbreak, said Global Justice Now director Nick Dearden, "the British government has spent more time actually stopping a pandemic treaty being agreed because it threatens Big Pharma power."
Policymakers in wealthy countries including the U.K. and the U.S. have objected to provisions in a pandemic treaty proposed by WHO, such as those that call for countries to donate vaccine doses to low-income countries or waive intellectual property laws for vaccines and treatments during a pandemic.
Such objections are "bad for all of us," said Dearden. "If we'd dealt with this internationally years ago, we could have prevented this dangerous new strain."
MSF called on WHO to accelerate its Emergency Use Listing (EUL) Procedure for two mpox vaccines that have been approved internationally, which would encourage manufacturers to increase production and allow agencies including the United Nations Children's Fund to distribute the vaccines.
The stockpiling of vaccines by "rich countries that do not need them," said economist Jayati Ghosh, "is exactly what the world does not need to confront this latest health threat."
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Sanders Proposes 'Moonshot' Bill to Combat Long Covid Crisis
"The legislation that we have introduced finally recognizes that long Covid is a public health emergency and provides an historic investment into research, development, and education," he said.
Aug 02, 2024
Over four months after seeking public comments on long Covid legislation, U.S. Sen. Bernie Sanders on Friday unveiled a bill to help tackle the crisis "that is affecting more than 22 million adults and 1 million children across the United States—and millions more around the globe."
Long Covid "can include a wide range of ongoing symptoms and conditions that can last weeks, months, or even years" after an initial infection, according to the U.S. Centers for Disease Control and Prevention. Symptoms can include brain fog, fatigue, heart palpitations, mood changes, muscle or joint pain, shortness of breath, and difficulty sleeping.
The Long Covid Research Moonshot Act of 2024 would provide the National Institutes of Health (NIH) with $1 billion in mandatory funding per year for a decade to support studies, the pursuit of treatments, and the expansion of care for U.S. patients impacted by the condition.
As Sanders' (I-Vt.) office highlighted, the bill would:
- Require the NIH to establish a long Covid database, advisory board, and a new grant process that would accelerate clinical trials;
- Fund information gathering and public health education;
- Require any new treatments developed by the NIH to be reasonably priced so that every patient can receive it;
- Fund multidisciplinary long Covid clinics that provide comprehensive, coordinated care—especially in underserved, disproportionately impacted communities; and
- Develop and implement best practices for clinical care and social services.
"For far too long, millions of Americans suffering from long Covid have had their symptoms dismissed or ignored—by the medical community, by the media, and by Congress," said Sanders, chair of the Senate Committee on Health, Education, Labor, and Pensions (HELP). "That is unacceptable and has got to change."
"The legislation that we have introduced finally recognizes that long Covid is a public health emergency and provides an historic investment into research, development, and education needed to counter the effects of this terrible disease," he continued. "Congress must act now to ensure treatments are developed and made available for Americans struggling with long Covid. Yes. It is time for a long Covid moonshot."
In addition to Sanders, the bill is backed by Sens. Tammy Duckworth (D-Ill.), Tim Kaine (D-Va.), Ed Markey (D-Mass.), Tina Smith (D-Minn.), and Peter Welch (D-Vt.). It also has support from over 45 groups including Body Politic, Covid-19 Longhauler Advocacy Project, Long Covid Alliance, Infectious Diseases Society of America, Marked by Covid, Mount Sinai Health System, National Partnership for Women and Families, and Patient-Led Research Collaborative (PLRC).
"The act is a historic piece of legislation," PLRC said on social media, sharing some details about the proposal. "We are so grateful for Sens. Sanders, Kaine, Markey, Welch, Duckworth, and Smith's leadership on #LongCovid, and for responding to the patient community's call with this incredible bill."
"This took a tremendous amount of work behind the scenes. PLRC is so honored to have been part of this process and so appreciative of everyone involved!" the group added. "This is a rare opportunity that most illnesses will never have and a chance that may not come again. In the coming months we will need the full support of the community and all allies to rally around this bill, and to call your representatives to support and co-sponsor this bill."
The groups #MEAction and Solve M.E. also support the legislation, and advocates for people with other diagnoses celebrated that the NIH initiative would be directed to "conduct comparative research to understand the similarities and differences between long Covid and other infection-associated chronic conditions with similar phenotypes, such as myalgic encephalomyelitis/chronic fatigue syndrome, postural orthostatic tachycardia syndrome, and post-treatment Lyme disease syndrome/persistent Lyme disease, and how activities funded by the program could improve understanding of such other conditions."
The bill also states that the program should "conduct comparative research to understand the similarities and differences between long Covid and severe, long-term effects from Covid-19 vaccinations," which were rolled out globally—though unequally and inadequately—during the pandemic.
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Did the US Government Under Trump Spread Vaccine Disinformation Around the World?
A few thoughts on an idiotic psyop that may have killed innocent people and blown back against our own citizens.
Jul 31, 2024
In June, Reutersreported on a hitherto secret U.S. program connected with the Covid-19 pandemic. In the spring of 2020, as the coronavirus rapidly spread throughout the world, our government sought to respond to Chinese disinformation which attempted to deflect responsibility for the virus’s origin by claiming that it had originated in a biological research lab at Fort Detrick, Maryland. What was our government’s plan? To fight fire with fire.
This was at the same time that the then-president of the Philippines, Rodrigo Duterte, was making noises about a closer relationship to China, even hinting that if China prioritized sending vaccine to his country, he would cede territory in the South China Sea to Beijing. Simultaneously, an element within the U.S. military in the Pacific was agitating Washington about keeping the Philippines on side and fighting the deluge of Chinese propaganda.
As a result, the Pentagon authorized a covert disinformation campaign against China, focusing on discrediting Chinese vaccine and protective medical equipment like masks. The channels of propaganda would be Twitter (now X), Facebook, and other social media. The campaign appears to have worked: the Philippines ended up with a very low vaccination rate in international comparison (in spite of Duterte’s efforts), and a high death rate.
While it is generally acknowledged that the Chinese vaccine (known as CoronaVac or Sinovac) is less effective, it is hardly useless: typically a 60-70-percent effectiveness versus the roughly 90-percent effectiveness of Western vaccines. Thus, it could have saved lives in the Philippines but for the U.S. disinformation campaign.
It is one more reason why Trump and his appointees should never be entrusted with public office. Will Congress ever investigate this misbegotten operation and finally nail down the chain of events?
It’s all there in the Reuters article, and there is no need to expatiate on the obvious immorality of the operation, quite apart from its colossal stupidity—at the same time U.S. public health officials were tearing out their hair trying to combat domestic Covid-19 disinformation, and doctors and nurses were risking their lives caring for terminally ill vaccine refusers, their government was pumping the same ideological poison into the minds of innocent people abroad. The nonchalant statement of an unnamed Pentagon official says it all: “We weren’t looking at this from a public health perspective. We were looking at how we could drag China through the mud.”
The report left a few dangling lose ends, however, that deserve further investigation by Congress and the Pentagon inspector general.
Are U.S. special forces out of control? The report says that the program was initiated after persistent lobbying by the then-commander of Special Operations Command Pacific, General Jonathan Braga. The article implies that he pleaded directly to Washington. Did his superiors at U.S. Pacific Command in Hawaii know what he was doing? Did they approve? We know from Reuters that various U.S. ambassadors in Southeast Asia did not approve, and they would ordinarily have overruled the general because it was a stupid idea that could harm diplomatic relations. But because the then-Secretary of Defense Mark Esper designated the propaganda campaign as a de facto wartime action, the diplomats’ objections could be disregarded.
U.S. special forces were vastly expanded during the wars in Iraq and Afghanistan and were given greater operational flexibility. They have also tended to produce loose cannons throughout the ranks. General Stanley McChrystal was special forces commander at the height of the Iraq war and later became commander of all coalition forces in Afghanistan. His career came to grief when he had the bad judgment to insult President Obama and other civilian leaders in front of a Rolling Stone reporter. Apparently, the civilian pukes in Washington lacked the general’s gung-ho attitude that with just a little more door-kicking and pyrotechnics, Afghanistan would be pacified—something that hadn’t happened since the Mongol invasions.
This kinetic mentality can get out of hand, as it did in 2017. Four Navy SEALs who were posted to the U.S. embassy in Mali, in a “juvenile” attempt to haze an Army special forces soldier, killed him. Their court martial, in a strange display of leniency, sentenced the most culpable perpetrator to only 10 years in prison, while one of the four defendants did not even receive a punitive discharge. The 10-year sentence was later vacated, with the defendant hiring a Trump lawyer to try to get him off the hook.
Ironically, vaccine refusal was the cause of another special forces stunt. Personnel from the Navy Special Warfare Command, including SEALs, not only declined to be vaccinated, but sued the Department of Defense. Their venue-shopping landed them in the Fort Worth court room of U.S. District Judge Reed O’Connor, a favorite destination for nutty conservative causes, and shockingly but not surprisingly, the judge ruled in favor of the plaintiffs. Ultimately, the Supreme Court blocked the judge’s ruling, but only insofar as it allowed the Navy to reassign, as opposed to discipline or discharge, the plaintiffs, while litigation continued.
What the personnel had done merited not merely reassignment or discharge, but potentially a court martial for the following: deliberately rendering themselves undeployable; endangering other service members; gross insubordination; and possibly even mutiny, as it was an organized action against their unit.
I have written before how religion is bandied about for political advantage by people whose own religious faith is ludicrously insincere. The justification of the SEALs—whose profession is to kill people—was a risible claim that deep Christian devotion prompted their refusal, advancing the heretofore undiscovered theological tenet that modification of their bodies by vaccine is an “affront to their Creator.” Apparently that doctrine exempts steroid abuse, which is common in the Navy’s special warfare community.
Even the military has begun to recognize that special forces may have become the tail that wags the dog—too big (bigger than the entire German army), diluted in quality, often operating outside the regular chain of command, and infected with a cowboy mentality. The mindless popular adulation, particularly of SEALs, has according to some observers had an adverse impact on civil-military relations. Perhaps we will always need door-kickers, but should they be overruling ambassadors in order to execute a cruel and asinine operation in a friendly country?
Who ultimately ordered the covert operation? The Reuters piece noted that Esper signed the directive to conduct the operation. The legality of his action rested on a provision in the 2019 defense authorization act permitting the military to conduct clandestine influence operations against other countries, including “outside of areas of active hostilities.”
This only raises more questions. Were the defense and intelligence committees of Congress, then controlled by the Democrats, duly notified of the disinformation campaign? If so, did the notification simply state that a covert psychological operation was underway, or did it provide enough details to make it clear that it was based on lies that could endanger the population of a friendly country? What was the reaction of Congress?
Perhaps we will always need door-kickers, but should they be overruling ambassadors in order to execute a cruel and asinine operation in a friendly country?
It seems unlikely that even as powerful a bureaucratic actor as the secretary of defense would order such a sensitive operation in defiance of the State Department without the guidance of those above him, or at least as a result of their signing off on his plan. The rules of Washington normally impel a person like Esper to seek cover for his actions. Accordingly, it is probable that he either notified the president directly or through the national security council of his order.
Then-President Trump had already directed the CIA in 2019 to conduct covert psychological operations inside China, so it is hardly a stretch to speculate that he would have had no problem approving DoD’s covert operation in the Philippines. It is one more reason why Trump and his appointees should never be entrusted with public office. Will Congress ever investigate this misbegotten operation and finally nail down the chain of events?
How do we know the operation did not blow back on the United States? The military is prohibited by law from conducting propaganda campaigns in the United States. But given the instant global connectedness of the internet, how could the Pentagon be so sure that its black propaganda campaigns in other countries wouldn’t leak back to the American population? They were, after all, using Twitter and Facebook accounts.
According to the U.S. Census Bureau, the Filipino population in the United States was 4.4 million in 2020, the third-largest Asian-American group. It is inconceivable that none of them would have had contact with friends and relatives in the Philippines who might have been gulled by the American disinformation. Had their contacts made them vaccine-hesitant, it would have exacerbated the already epidemic anti-vaccine movement here.
Why did it take so long to shut down the program? Shortly after the inauguration, representatives from Facebook arranged a meeting with incoming Biden administration officials to complain about the covert program, which contradicted the company’s policy against spreading vaccine disinformation. The officials were properly horrified, but again, there are loose ends to the Reuters story.
Why hadn’t the new administration learned about the program through Pentagon channels already during the transition? Why did it take until the spring of 2021 to order DoD to shut it down? And in spite of the order, why did the program linger through the summer? Was the Biden administration lax in its follow-up, or was the Pentagon out of control?
Over the decades, the U.S. military has conducted numerous programs of breathtaking stupidity: the above-ground nuclear tests of the 1950s that exposed draftees to atomic radiation, dumping thousands of tons of Agent Orange defoliant over Indochina during the 1960s, the toxic burn pits of the Iraq war. Civilian leadership in this country needs to shed its adolescent awe of martial exploits and gain firm control over a very dangerous weapon.Keep ReadingShow Less
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