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"This ill-considered decision will sow further chaos and confusion and erode confidence in immunizations," warned the American Academy of Pediatrics president.
Leading US medical groups were among the critics who forcefully condemned the Trump administration's Monday overhaul of federal vaccine recommendations for every child in the country.
Doctors and public health advocates have been warning of such changes since the US Senate confirmed President Donald Trump's pick to lead the Department of Health and Human Services (HHS), vaccine conspiracy theorist Robert F. Kennedy Jr., nearly a year ago.
Last month, in a presidential memorandum, Trump directed Kennedy and Deputy Secretary of Health and Human Services Jim O'Neill, who is also acting director of the Centers for Disease Control and Prevention (CDC), "to review best practices from peer, developed countries for core childhood vaccination recommendations."
HHS said in a Monday statement that "after consulting with health ministries of peer nations, considering the assessment's findings, and reviewing the decision memo" presented by National Institutes of Health Director Dr. Jay Bhattacharya, Food and Drug Commissioner Dr. Marty Makary, and Centers for Medicare and Medicaid Services Administrator Dr. Mehmet Oz, O'Neill "formally accepted the recommendations and directed the CDC to move forward with implementation."
O'Neill claimed that "the data support a more focused schedule" and the HHS secretary said that "after an exhaustive review of the evidence, we are aligning the US childhood vaccine schedule with international consensus while strengthening transparency and informed consent," but leading experts pushed back against their framing.
“Changes of this magnitude require careful review, expert and public input, and clear scientific justification. That level of rigor and transparency was not part of this decision."
Dr. Sandra Adamson Fryhofer, an American Medical Association trustee, said in a statement that the AMA "is deeply concerned by recent changes to the childhood immunization schedule that affects the health and safety of millions of children. Vaccination policy has long been guided by a rigorous, transparent scientific process grounded in decades of evidence showing that vaccines are safe, effective, and lifesaving."
“Changes of this magnitude require careful review, expert and public input, and clear scientific justification. That level of rigor and transparency was not part of this decision," she continued. "When long-standing recommendations are altered without a robust, evidence-based process, it undermines public trust and puts children at unnecessary risk of preventable disease."
"The scientific evidence remains unchanged, and the AMA supports continued access to childhood immunizations recommended by national medical specialty societies," the doctor added. "We urge federal health leaders to recommit to a transparent, evidence-based process that puts children's health and safety first and reflects the realities of our nation's disease burden."
American Academy of Pediatrics (AAP) President Dr. Andrew D. Racine was similarly critical of the "dangerous and unnecessary" move, stressing that "the long-standing, evidence-based approach that has guided the US immunization review and recommendation process remains the best way to keep children healthy and protect against health complications and hospitalizations."
As Racine explained:
Said to be modeled in part after Denmark's approach, the new recommendations issued today by the US Centers for Disease Control and Prevention no longer recommend routine immunization for many diseases with known impacts on America's children, such as hepatitis A and B, rotavirus, respiratory syncytial virus (RSV), flu, and meningococcal disease. AAP continues to recommend that children be immunized against these diseases, and for good reason; thanks to widespread childhood immunizations, the United States has fewer pediatric hospitalizations and fewer children facing serious health challenges than we would without this community protection.
The United States is not Denmark, and there is no reason to impose the Danish immunization schedule on America's families. America is a unique country, and Denmark's population, public health infrastructure, and disease-risk differ greatly from our own.
At a time when parents, pediatricians, and the public are looking for clear guidance and accurate information, this ill-considered decision will sow further chaos and confusion and erode confidence in immunizations. This is no way to make our country healthier.
The doctor urged parents who "have questions about vaccines or anything else" to speak with their pediatricians and pledged that the AAP "will continue to stand up for children, just as we have done for the past 95 years."
Dr. Robert Steinbrook, Health Research Group director at the consumer advocacy organization Public Citizen, also slammed Kennedy and his deputies for starting out "2026 by escalating and accelerating their mindless assault on the childhood and adolescent immunization schedule."
"Extreme and arbitrary changes to the childhood vaccination schedule without full public discussion and scientific and evidence-based vetting put children and families at risk and undermine public health," Steinbrook said. "The uncalled-for changes are likely to further erode trust in vaccines and decrease immunization rates, rather than increase confidence or boost vaccine uptake, as federal health officials assert. Once again, medical professional societies and states must act to prevent suffering and death from preventable diseases."
As the Associated Press noted Monday: "States, not the federal government, have the authority to require vaccinations for schoolchildren. While CDC requirements often influence those state regulations, some states have begun creating their own alliances to counter the Trump administration's guidance on vaccines."
Lawrence Gostin, founding chair of the O'Neill Institute for National and Global Health Law Georgetown University, predicted that "red states will mostly follow HHS guidance. Blue states will certainly keep the current schedule. We'll see a checkerboard of different rules across America. Infectious diseases will surge as pathogens don't respect state borders."
Ripping the CDC's move as "reckless and lawless," Gostin added that "RFK Jr. is plunging the nation into uncertainty and confusion. Will pharmacies and pediatricians offer vaccines without clear recommendations? Will insurers cover vaccines? Will school boards worry about liability? Needless hospitalizations and deaths are all but certain to occur."
The US is at risk of losing its measles-eradicated status early next year, according to Scientific American.
US Rep. Pramila Jayapal on Friday demanded that the Trump administration "stop lying and follow the science" as an outbreak of measles in South Carolina grew and officials warned that low vaccination rates in the affected area likely mean the crisis will continue worsening.
Since the outbreak began in October in Spartanburg County, near the state's northern border, the highly infectious disease has sickened at least 129 people. The vast majority of people who have been infected have not been inoculated against measles, which is 97% preventable via the measles, mumps, and rubella (MMR) shot—which has been erroneously attacked for years by anti-vaccine activists including Health and Human Services Secretary Robert F. Kennedy Jr.
As President Donald Trump and Kennedy "push deadly anti-vaccine conspiracy theories, measles is making a comeback across America," said Jayapal (D-Wash.) on Friday. "People will die because of this."
At least three people, including two children, have already died this year in US measles outbreaks
More than 1,900 measles cases and 47 outbreaks have been reported across the country in 2025, compared with 285 cases across 16 outbreaks last year.
In South Carolina, more than 250 people have been exposed to the disease in schools, a healthcare facility, and a church, forcing dozens of unvaccinated children to quarantine for 21 days; some were exposed twice and had to be isolated for two separate three-week periods.
“That’s a significant amount of time,” Linda Bell, the state's epidemiologist, said at a recent press conference. “Vaccination continues to be the best way to prevent the disruption that measles is causing to people’s education, to employment.”
But Spartanburg County's ongoing outbreak is being driven by “lower-than-hoped-for vaccination coverage,” Bell said.
Public health experts consider a 95% vaccination rate to be the level at which the spread of measles can be eliminated in a community. Only about 90% of students in the county had all required childhood immunizations. South Carolina allows religious exemptions for school immunization requirements. Many of the schools where students have quarantined have vaccination rates "well below 90%," the New York Times reported.
Across South Carolina, MMR vaccination rates among schoolchildren has fallen significantly since 2020, from 96% to 93.5%.
Kennedy has been a longtime denier of vaccine science. In 2019, his anti-vaccine group, Children's Health Defense, tried to sue New York state over its vaccine requirement, which is one of just five in the country that doesn't allow for nonmedical exemptions.
In April, Kennedy visited a Texas community where two unvaccinated children had died of measles and acknowledged in a social media post that "the most effective way to prevent the spread of measles is the MMR vaccine."
“Vaccination continues to be the best way to prevent the disruption that measles is causing to people’s education, to employment.”
But during his visit he also promoted, without evidence, two therapeutic treatments that one vaccine expert told NPR are "valueless" in treating measles. In 2023 Kennedy told podcaster Joe Rogan that the vaccine was not linked to a decline in deaths.
He has recently continued fueling overall skepticism about immunizations, with the Centers for Disease Control and Prevention (CDC) panel he assembled advising that newborn babies whose mothers test negative for hepatitis B should not receive a dose of a vaccine for the disease—sparking fear among public health experts that major progress in reducing childhood cases of the disease over the past three decades will be reversed.
In November the CDC website was changed to say a link between vaccines and autism—a theory that has long been debunked—cannot be ruled out. Two months earlier, as measles cases surged in another outbreak around the Utah-Arizona border, Trump called for combination children's vaccines like the MMR to be split up into separate shots—a call made decades ago by Dr. Andrew Wakefield, who lost his medical license over his 1988 study that linked autism to the combination vaccine, which was later retracted.
High vaccine rates allowed the US to declare measles eliminated in 2000, but Scientific American reported Thursday that the current measles outbreaks are bringing the US "toward losing its measles-free status by early next year."
The worsening measles outbreak in South Carolina, said Sen. Ed Markey (D-Mass.), "is yet another horrifying consequence of Trump and RFK Jr.'s Make America Sick Agenda."
Republican Gov. Henry McMaster has urged residents to be vaccinated against measles, but said on Thursday, "We are not going to do mandates on people to go get vaccinated."
Andrew Nixon, a spokesperson for the US Health and Human Services Department, also continued to suggest that vaccination is principally a matter of personal liberty rather than public health, telling the New York Times that people in the affected community in South Carolina should talk to their doctors about "what is best for them."
On Thursday, Senate Health, Education, Labor, and Pensions Committee Ranking Member Bernie Sanders (I-Vt.) said that along with the Republican Party's vote against extending Affordable Care Act subsidies, the Trump administration is raising questions about its push to "Make America Health Again" as it undermines "lifesaving vaccines and spark[s] disease outbreaks."
"The Trump administration," he said, "is endangering the health of the American people."
"Failure to conduct an oversight hearing on Secretary Kennedy's actions would be an abdication of our responsibility—both from a moral perspective and as a matter of sound public health policy."
On the heels of a federal panel appointed by US Health and Human Services Secretary Robert F. Kennedy Jr. voting to reverse a recommendation that newborns receive the hepatitis B vaccine, Sen. Bernie Sanders led a Tuesday call for the HHS leader to be hauled before a relevant congressional committee to answer for his actions that "undermine the health and well-being of the American people and people throughout the world."
In a letter signed by Democrats on the Senate Health, Education, Labor, and Pensions (HELP) Committee and Sanders (I-Vt.), its ranking member, the lawmakers wrote to Republican Chair Bill Cassidy (La.), a medical doctor, to argue that "Kennedy has waged an unprecedented war on science and vaccines that have saved millions of lives," and demand his testimony.
The letter highlights Kennedy directing the US Centers for Disease Control and Prevention "to publish false information on its website suggesting that childhood vaccines cause autism," ousting a CDC director "who refused to rubber-stamp his dangerous and unsubstantiated" recommendations, spreading misinformation about the measles vaccine during an outbreak, and defunding research "that will leave us woefully unprepared for future pandemics and public health emergencies."
Kennedy has also "packed a critical scientific body, the Advisory Committee on Immunization Practices (ACIP), with vaccine deniers, completely upending the rigorous scientific process for reviewing and recommending vaccines to the public despite a commitment he made to you that ACIP would be 'maintained without changes,'" the letter continues, citing last week's hepatitis B vote.
"Mr. Chairman: Holding an oversight hearing on Secretary Kennedy’s ill-conceived actions is more important now than ever," argued Sanders and Democratic Sens. Angela Alsobrooks (Md.), Tammy Baldwin (Wis.), Lisa Blunt Rochester (Del.), Maggie Hassan (NH), John Hickenlooper (Colo.), Tim Kaine (Va.), Andy Kim (NJ), Ed Markey (Mass.), Chris Murphy (Conn.), and Patty Murray (Wash.).
"Under Secretary Kennedy;s leadership, over 1,700 people have been infected with measles. Whooping cough cases are surging nationwide, and concerns about a severe flu season continue to grow. Vaccination rates across the country are falling. Children are dying from illnesses that vaccines could have prevented," the senators stressed.
"Secretary Kennedy's response to these crises has been to spread misinformation, end campaigns encouraging flu vaccinations, fire officials who disagree with him, and place individuals with significant conflicts of interest in positions of power—completely undermining Americans' faith in our nation's public health institutions," they wrote.
The senators pointed out that "dozens of scientific and medical groups" have called for Kennedy's resignation or removal, as have more than 1,000 current and former HHS staffers. They also noted a September warning from nine former CDC directors that the secretary "is endangering every American's health," a similar joint statement the following month by ex-surgeons general, and another this month from a dozen previous Food and Drug Administration commissioners.
The letter also references Cassidy's comments about ACIP, the safety and effectiveness of vaccines, and Kennedy's supposed commitment during the confirmation process to come before the HELP Committee on a quarterly basis, which hasn't happened.
"Failure to conduct an oversight hearing on Secretary Kennedy's actions would be an abdication of our responsibility—both from a moral perspective and as a matter of sound public health policy," the letter argues, calling for his testimony as soon as possible.