A worker sprays herbicide during a Roadside Invasive Management Workshop held July 29, 2025 at the Winchester Department of Public Works in Connecticut.
‘Unconscionable, Immoral, and Illegal’: Lawsuit Targets Trump Approval of Cancer-Causing Forever Chemical
“While everyone’s distracted by the Trump administration’s erratic actions on the world stage, it keeps approving dangerous forever pesticides right here on our own soil."
Environmental groups have sued the Trump administration, alleging the Environmental Protection Agency approved a potentially cancer-causing "forever chemical" for use as an herbicide without fully assessing the risk.
The petition was filed Friday in the US Court of Appeals for the 9th Circuit by the Center for Food Safety, the Center for Biological Diversity, and Pesticide Action & Agroecology Network North America, who asked the court to throw out the EPA's June 30 approval of trifludimoxazin and six products containing it for use on a wide range of crops including corn, wheat, soybeans, and apples.
Trifludimoxazin is part of the family of per- and polyfluoroalkyl substances, synthetic chemicals with strong carbon-fluorine bonds that can take years to fully break down, earning them the nickname "forever chemicals."
The trifludimoxazin was initially approved in 2021 during the Biden administration. But the company agreed to stop selling the product the following year after environmental groups sued, citing its potential to cause cancer and harm to threatened and endangered fish. But the Trump EPA last year proposed registering it again for widespread use and issued a final approval in June.
The groups argue that the EPA approved the use of trifludimoxazin without accounting for evidence that the pesticide could cause cancer and harm wildlife and ecosystems.
The EPA itself has acknowledged that the chemical could harm many endangered and threatened species, including posing chronic risks to bees and other invertebrates. Meanwhile, rodent studies have found that at high doses, the chemical can cause thyroid tumors and adverse effects on the liver and reproductive systems.
The chemical, which blocks an enzyme in plants needed for growth, has been described as 10 times as potent as dicamba, another weedkiller used on soybeans and cotton, whose products have caused millions of acres of unintended crop damage since its approval in 2017.
But though the EPA's own guidance states that carcinogenic effects in animals could point to human risk, the agency stated that its final risk assessment found “no human health risks of concern."
The plaintiffs argue that the EPA did not take all the proper steps to reach this conclusion, having failed to quantify the chemical's danger, especially when combined with exposure to other approved chemicals.
“Trifludimoxazin is a likely human carcinogen that belongs to a family of weedkillers that also causes reproductive harm, birth defects, and neurological deficits in animal studies,” said Bill Freese, science director at the Center for Food Safety. “As if the health threats weren’t enough, this incredibly potent herbicide can drift to stunt crops and wild plants hundreds of yards from a sprayed field, while runoff threatens wetland plants. Potent biocides like this have no business on the American landscape.”
The lawsuit also notes that two of the approved trifludimoxazin products combine it with another toxic herbicide called saflufenacil, meaning that farmworkers who apply the chemicals could be exposed to the effects of both at once. The plaintiffs said the EPA did not evaluate the risk that would be posed to farmworkers who are exposed to these chemicals.
“While everyone’s distracted by the Trump administration’s erratic actions on the world stage, it keeps approving dangerous forever pesticides right here on our own soil,” said Nathan Donley, environmental health science director at the Center for Biological Diversity. “It’s unconscionable, immoral, and illegal. Our kids and grandkids deserve better than to be saddled with pollution that never goes away.”
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Environmental groups have sued the Trump administration, alleging the Environmental Protection Agency approved a potentially cancer-causing "forever chemical" for use as an herbicide without fully assessing the risk.
The petition was filed Friday in the US Court of Appeals for the 9th Circuit by the Center for Food Safety, the Center for Biological Diversity, and Pesticide Action & Agroecology Network North America, who asked the court to throw out the EPA's June 30 approval of trifludimoxazin and six products containing it for use on a wide range of crops including corn, wheat, soybeans, and apples.
Trifludimoxazin is part of the family of per- and polyfluoroalkyl substances, synthetic chemicals with strong carbon-fluorine bonds that can take years to fully break down, earning them the nickname "forever chemicals."
The trifludimoxazin was initially approved in 2021 during the Biden administration. But the company agreed to stop selling the product the following year after environmental groups sued, citing its potential to cause cancer and harm to threatened and endangered fish. But the Trump EPA last year proposed registering it again for widespread use and issued a final approval in June.
The groups argue that the EPA approved the use of trifludimoxazin without accounting for evidence that the pesticide could cause cancer and harm wildlife and ecosystems.
The EPA itself has acknowledged that the chemical could harm many endangered and threatened species, including posing chronic risks to bees and other invertebrates. Meanwhile, rodent studies have found that at high doses, the chemical can cause thyroid tumors and adverse effects on the liver and reproductive systems.
The chemical, which blocks an enzyme in plants needed for growth, has been described as 10 times as potent as dicamba, another weedkiller used on soybeans and cotton, whose products have caused millions of acres of unintended crop damage since its approval in 2017.
But though the EPA's own guidance states that carcinogenic effects in animals could point to human risk, the agency stated that its final risk assessment found “no human health risks of concern."
The plaintiffs argue that the EPA did not take all the proper steps to reach this conclusion, having failed to quantify the chemical's danger, especially when combined with exposure to other approved chemicals.
“Trifludimoxazin is a likely human carcinogen that belongs to a family of weedkillers that also causes reproductive harm, birth defects, and neurological deficits in animal studies,” said Bill Freese, science director at the Center for Food Safety. “As if the health threats weren’t enough, this incredibly potent herbicide can drift to stunt crops and wild plants hundreds of yards from a sprayed field, while runoff threatens wetland plants. Potent biocides like this have no business on the American landscape.”
The lawsuit also notes that two of the approved trifludimoxazin products combine it with another toxic herbicide called saflufenacil, meaning that farmworkers who apply the chemicals could be exposed to the effects of both at once. The plaintiffs said the EPA did not evaluate the risk that would be posed to farmworkers who are exposed to these chemicals.
“While everyone’s distracted by the Trump administration’s erratic actions on the world stage, it keeps approving dangerous forever pesticides right here on our own soil,” said Nathan Donley, environmental health science director at the Center for Biological Diversity. “It’s unconscionable, immoral, and illegal. Our kids and grandkids deserve better than to be saddled with pollution that never goes away.”
Environmental groups have sued the Trump administration, alleging the Environmental Protection Agency approved a potentially cancer-causing "forever chemical" for use as an herbicide without fully assessing the risk.
The petition was filed Friday in the US Court of Appeals for the 9th Circuit by the Center for Food Safety, the Center for Biological Diversity, and Pesticide Action & Agroecology Network North America, who asked the court to throw out the EPA's June 30 approval of trifludimoxazin and six products containing it for use on a wide range of crops including corn, wheat, soybeans, and apples.
Trifludimoxazin is part of the family of per- and polyfluoroalkyl substances, synthetic chemicals with strong carbon-fluorine bonds that can take years to fully break down, earning them the nickname "forever chemicals."
The trifludimoxazin was initially approved in 2021 during the Biden administration. But the company agreed to stop selling the product the following year after environmental groups sued, citing its potential to cause cancer and harm to threatened and endangered fish. But the Trump EPA last year proposed registering it again for widespread use and issued a final approval in June.
The groups argue that the EPA approved the use of trifludimoxazin without accounting for evidence that the pesticide could cause cancer and harm wildlife and ecosystems.
The EPA itself has acknowledged that the chemical could harm many endangered and threatened species, including posing chronic risks to bees and other invertebrates. Meanwhile, rodent studies have found that at high doses, the chemical can cause thyroid tumors and adverse effects on the liver and reproductive systems.
The chemical, which blocks an enzyme in plants needed for growth, has been described as 10 times as potent as dicamba, another weedkiller used on soybeans and cotton, whose products have caused millions of acres of unintended crop damage since its approval in 2017.
But though the EPA's own guidance states that carcinogenic effects in animals could point to human risk, the agency stated that its final risk assessment found “no human health risks of concern."
The plaintiffs argue that the EPA did not take all the proper steps to reach this conclusion, having failed to quantify the chemical's danger, especially when combined with exposure to other approved chemicals.
“Trifludimoxazin is a likely human carcinogen that belongs to a family of weedkillers that also causes reproductive harm, birth defects, and neurological deficits in animal studies,” said Bill Freese, science director at the Center for Food Safety. “As if the health threats weren’t enough, this incredibly potent herbicide can drift to stunt crops and wild plants hundreds of yards from a sprayed field, while runoff threatens wetland plants. Potent biocides like this have no business on the American landscape.”
The lawsuit also notes that two of the approved trifludimoxazin products combine it with another toxic herbicide called saflufenacil, meaning that farmworkers who apply the chemicals could be exposed to the effects of both at once. The plaintiffs said the EPA did not evaluate the risk that would be posed to farmworkers who are exposed to these chemicals.
“While everyone’s distracted by the Trump administration’s erratic actions on the world stage, it keeps approving dangerous forever pesticides right here on our own soil,” said Nathan Donley, environmental health science director at the Center for Biological Diversity. “It’s unconscionable, immoral, and illegal. Our kids and grandkids deserve better than to be saddled with pollution that never goes away.”