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Smoke billows from the site of a UPS cargo plane crash near Louisville Muhammad Ali International Airport in Kentucky on November 4, 2025.
(Photo by Stephen Cohen/Getty Images)
UPS Cargo Plane Crash at Louisville Airport Sparks Massive Fire
Police announced a shelter-in-place order for "all areas north of the airport to the Ohio River."
Nov 04, 2025
This is a developing story… Please check back for updates…
Aerial footage showed plumes of black smoke and flames around the Louisville Muhammad Ali International Airport in Kentucky after a UPS plane crashed during its departure on Tuesday evening.
The Federal Aviation Administration said on social media that UPS Flight 2976—a McDonnell Douglas MD-11 bound for Daniel K. Inouye International Airport in Honolulu, Hawaii—crashed around 5:15 pm local time. The agency added that the FAA and National Transportation Safety Board will investigate, with the NTSB providing all updates.
The Louisville Metro Police Department confirmed that the LMPD and multiple other agencies were responding to the scene, where there are "injuries reported."
LMPD initially announced a shelter-in-place order "for all locations within five miles of the airport," which was then expanded to "all areas north of the airport to the Ohio River."
The airport—which confirmed that "the airfield is closed" after the crash—is the UPS global hub. The shipping giant said in a statement that there were three crewmembers onboard and "at this time, we have not confirmed any injuries/casualties."
"UPS will release more facts as they become available, but the National Transportation Safety Board is in charge of the investigation and will be the primary source of information about the official investigation," the company added.
As CNN reported Tuesday:
The McDonnell Douglas MD-11F is a freight transport aircraft manufactured originally by McDonnell Douglas and later by Boeing. The aircraft is primarily flown by FedEx Express, Lufthansa Cargo, and UPS Airlines for cargo.
The plane also served as a popular wide-bodied passenger airplane after it was first flown in 1990. The aircraft involved in Tuesday's crash was built in 1991.
As fuel costs increased for the three engine jets many of them were converted to freighters. The plane can take off weighing in at a maximum 633,000 pounds and carrying more than 38,000 gallons of fuel, according to Boeing, which bought McDonnell Douglass.
The International Brotherhood of Teamsters said that it "is monitoring this developing tragic event on the ground," and "as this horrific scene is being investigated, prayers on behalf of our entire international union are with those killed, injured, and affected, including their families, co-workers, and loved ones."
Louisville Mayor Craig Greenberg said that he and his wife, Rachel, "are praying for victims of the UPS plane that crashed."
"We have every emergency agency responding to the scene," the Democrat added. "There are multiple injuries and the fire is still burning. There are many road closures in the area—please avoid the scene."
Democratic Kentucky Gov. Andy Beshear, who is headed to Louisville for a briefing with the mayor, said, "Please pray for the pilots, crew, and everyone affected."
Republican President Donald Trump's transportation secretary, Sean Duffy, similarly said, "Please join me in prayer for the Louisville community and flight crew impacted by this horrific crash."
During a press conference earlier on Tuesday, Duffy had warned of "mass chaos" if the ongoing government shutdown continues, saying: "You will see mass flight delays. You'll see mass cancellations, and you may see us close certain parts of the airspace, because we just cannot manage it because we don't have the air traffic controllers."
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andy beshearfederal aviation administrationkentuckynational transportation safety boardsean duffyupslouisville
This is a developing story… Please check back for updates…
Aerial footage showed plumes of black smoke and flames around the Louisville Muhammad Ali International Airport in Kentucky after a UPS plane crashed during its departure on Tuesday evening.
The Federal Aviation Administration said on social media that UPS Flight 2976—a McDonnell Douglas MD-11 bound for Daniel K. Inouye International Airport in Honolulu, Hawaii—crashed around 5:15 pm local time. The agency added that the FAA and National Transportation Safety Board will investigate, with the NTSB providing all updates.
The Louisville Metro Police Department confirmed that the LMPD and multiple other agencies were responding to the scene, where there are "injuries reported."
LMPD initially announced a shelter-in-place order "for all locations within five miles of the airport," which was then expanded to "all areas north of the airport to the Ohio River."
The airport—which confirmed that "the airfield is closed" after the crash—is the UPS global hub. The shipping giant said in a statement that there were three crewmembers onboard and "at this time, we have not confirmed any injuries/casualties."
"UPS will release more facts as they become available, but the National Transportation Safety Board is in charge of the investigation and will be the primary source of information about the official investigation," the company added.
As CNN reported Tuesday:
The McDonnell Douglas MD-11F is a freight transport aircraft manufactured originally by McDonnell Douglas and later by Boeing. The aircraft is primarily flown by FedEx Express, Lufthansa Cargo, and UPS Airlines for cargo.
The plane also served as a popular wide-bodied passenger airplane after it was first flown in 1990. The aircraft involved in Tuesday's crash was built in 1991.
As fuel costs increased for the three engine jets many of them were converted to freighters. The plane can take off weighing in at a maximum 633,000 pounds and carrying more than 38,000 gallons of fuel, according to Boeing, which bought McDonnell Douglass.
The International Brotherhood of Teamsters said that it "is monitoring this developing tragic event on the ground," and "as this horrific scene is being investigated, prayers on behalf of our entire international union are with those killed, injured, and affected, including their families, co-workers, and loved ones."
Louisville Mayor Craig Greenberg said that he and his wife, Rachel, "are praying for victims of the UPS plane that crashed."
"We have every emergency agency responding to the scene," the Democrat added. "There are multiple injuries and the fire is still burning. There are many road closures in the area—please avoid the scene."
Democratic Kentucky Gov. Andy Beshear, who is headed to Louisville for a briefing with the mayor, said, "Please pray for the pilots, crew, and everyone affected."
Republican President Donald Trump's transportation secretary, Sean Duffy, similarly said, "Please join me in prayer for the Louisville community and flight crew impacted by this horrific crash."
During a press conference earlier on Tuesday, Duffy had warned of "mass chaos" if the ongoing government shutdown continues, saying: "You will see mass flight delays. You'll see mass cancellations, and you may see us close certain parts of the airspace, because we just cannot manage it because we don't have the air traffic controllers."
This is a developing story… Please check back for updates…
Aerial footage showed plumes of black smoke and flames around the Louisville Muhammad Ali International Airport in Kentucky after a UPS plane crashed during its departure on Tuesday evening.
The Federal Aviation Administration said on social media that UPS Flight 2976—a McDonnell Douglas MD-11 bound for Daniel K. Inouye International Airport in Honolulu, Hawaii—crashed around 5:15 pm local time. The agency added that the FAA and National Transportation Safety Board will investigate, with the NTSB providing all updates.
The Louisville Metro Police Department confirmed that the LMPD and multiple other agencies were responding to the scene, where there are "injuries reported."
LMPD initially announced a shelter-in-place order "for all locations within five miles of the airport," which was then expanded to "all areas north of the airport to the Ohio River."
The airport—which confirmed that "the airfield is closed" after the crash—is the UPS global hub. The shipping giant said in a statement that there were three crewmembers onboard and "at this time, we have not confirmed any injuries/casualties."
"UPS will release more facts as they become available, but the National Transportation Safety Board is in charge of the investigation and will be the primary source of information about the official investigation," the company added.
As CNN reported Tuesday:
The McDonnell Douglas MD-11F is a freight transport aircraft manufactured originally by McDonnell Douglas and later by Boeing. The aircraft is primarily flown by FedEx Express, Lufthansa Cargo, and UPS Airlines for cargo.
The plane also served as a popular wide-bodied passenger airplane after it was first flown in 1990. The aircraft involved in Tuesday's crash was built in 1991.
As fuel costs increased for the three engine jets many of them were converted to freighters. The plane can take off weighing in at a maximum 633,000 pounds and carrying more than 38,000 gallons of fuel, according to Boeing, which bought McDonnell Douglass.
The International Brotherhood of Teamsters said that it "is monitoring this developing tragic event on the ground," and "as this horrific scene is being investigated, prayers on behalf of our entire international union are with those killed, injured, and affected, including their families, co-workers, and loved ones."
Louisville Mayor Craig Greenberg said that he and his wife, Rachel, "are praying for victims of the UPS plane that crashed."
"We have every emergency agency responding to the scene," the Democrat added. "There are multiple injuries and the fire is still burning. There are many road closures in the area—please avoid the scene."
Democratic Kentucky Gov. Andy Beshear, who is headed to Louisville for a briefing with the mayor, said, "Please pray for the pilots, crew, and everyone affected."
Republican President Donald Trump's transportation secretary, Sean Duffy, similarly said, "Please join me in prayer for the Louisville community and flight crew impacted by this horrific crash."
During a press conference earlier on Tuesday, Duffy had warned of "mass chaos" if the ongoing government shutdown continues, saying: "You will see mass flight delays. You'll see mass cancellations, and you may see us close certain parts of the airspace, because we just cannot manage it because we don't have the air traffic controllers."
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