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One critic charged that Trump's earlier deals with pharmaceutical companies "just nibble around the margins in terms of what is really driving high prices for prescription drugs in the US."
President Donald Trump in recent months has made ludicrously false claims about his administration slashing prescription drug prices in the US by as much as 600%, which would entail pharmaceutical companies paying people to use their products.
In reality, reported Reuters on Wednesday, drugmakers are planning to raise prices on hundreds of drugs in 2026.
Citing data from healthcare research firm 3 Axis Advisors, Reuters wrote that at least 350 branded medications are set for price hikes next year, including "vaccines against COVID, RSV, and shingles," as well as the "blockbuster cancer treatment Ibrance."
The total projected number of drugs seeing price increases next year is significantly higher than in 2025, when 3 Axis Advisors estimated that pharmaceutical companies raised prices on 250 medications.
The median price increase for drugs next year is projected at 4%, roughly the same as in 2025.
Reuters also found that some of the companies raising prices on their drugs are the same ones who struck deals with Trump to lower the costs of a limited number of prescriptions earlier this year, including Novartis, Pfizer, Boehringer Ingelheim, and GSK.
In announcing the deals with the pharmaceutical companies, Trump declared that "starting next year, American drug prices will come down fast and furious and will soon be the lowest in the developed world."
But Dr. Benjamin Rome, a health policy researcher at Brigham and Women's Hospital in Boston, told Reuters that the projected savings for Americans under the Trump deals are a drop in the bucket compared with the continued price hikes on other drugs.
"These deals are being announced as transformative when, in fact, they really just nibble around the margins in terms of what is really driving high prices for prescription drugs in the US," Rome explained.
Merith Basey, CEO of Patients For Affordable Drugs Now, a patient advocacy organization focused exclusively on lowering the cost of medications, also said she was unimpressed by Trump's deals with drugmakers.
"Voluntary agreements with drug companies—especially when key details remain undisclosed—are no substitute for durable, system-wide reforms," she said earlier this month. "Patients are overwhelmingly calling on Congress to do more to lower prescription drug prices by holding Big Pharma accountable and addressing the root causes of high drug prices, because drugs don’t work if people can’t afford them."
"Patients are overwhelmingly calling on Congress to do more to lower prescription drug prices by holding Big Pharma accountable and addressing the root causes of high drug prices," said one campaigner.
"Starting next year, American drug prices will come down fast and furious and will soon be the lowest in the developed world," President Donald Trump claimed Friday as the White House announced agreements with nine pharmaceutical manufacturers.
The administration struck most favored nation (MFN) pricing deals with Amgen, Bristol Myers Squibb, Boehringer Ingelheim, Genentech, Gilead Sciences, GSK, Merck, Novartis, and Sanofi. The president—who has launched the related TrumpRx.gov—previously reached agreements with AstraZeneca, EMD Serono, Eli Lilly, Novo Nordisk, and Pfizer.
"The White House said it has made MFN deals with 14 of the 17 biggest drug manufacturers in the world," CBS News noted Friday. "The three drugmakers that were not part of the announcement are AbbVie, Johnson & Johnson, and Regeneron, but the president said that deals involving the remaining three could be announced at another time."
However, as Trump and congressional Republicans move to kick millions of Americans off of Medicaid and potentially leave millions more uninsured because they can't afford skyrocketing premiums for Affordable Care Act (ACA) plans, some critics suggested that the new drug deals with Big Pharma are far from enough.
"When 47% of Americans are concerned they won't be able to afford a healthcare cost next year, steps to reduce drug prices for patients are welcomed, especially by patients who rely on one of the overpriced essential medicines named in today's announcement," said Merith Basey, CEO of Patients for Affordable Drugs Now, in a statement.
"But voluntary agreements with drug companies—especially when key details remain undisclosed—are no substitute for durable, system-wide reforms," Basey stressed. "Patients are overwhelmingly calling on Congress to do more to lower prescription drug prices by holding Big Pharma accountable and addressing the root causes of high drug prices, because drugs don't work if people can't afford them."
As the New York Times reported Friday:
Drugs that will be made available in this way include Amgen's Repatha, for lowering cholesterol, at $239 a month; GSK's asthma inhaler, Advair Diskus, at $89 a month; and Merck's diabetes medication Januvia, at $100 a month.
Many of these drugs are nearing the end of their patent protection, meaning that the arrival of low-cost generic competition would soon have prompted manufacturers to lower their prices.
In other cases, the direct-buy offerings are very expensive and out of reach for most Americans.
For example, Gilead will offer Epclusa, a three-month regimen of pills that cures hepatitis C, for $2,492 a month on the site. Most patients pay far less using insurance or with help from patient assistance programs. Gilead says on its website that "typically a person taking Epclusa pays between $0 and $5 per month" with commercial insurance or Medicare.
While medication prices are a concern for Americans who face rising costs for everything from groceries to utility bills, the outcome of the ongoing battle on Capitol Hill over ACA tax credits—which are set to expire at the end of the year—is expected to determine how many people can even afford to buy health insurance for next year.
The ACA subsidies fight—which Republicans in the US House of Representatives ignored in the bill they passed this week before leaving Capitol Hill early—has renewed calls for transitioning the United States from its current for-profit healthcare system to Medicare for All.
"At the heart of our healthcare crisis is one simple truth: Corporations have too much power over our lives," Rep. Pramila Jayapal (D-Wash.), former chair of the Congressional Progressive Caucus, said on social media Friday. "Medicare for All is how we take our power back and build a system that puts people over profits."
Jayapal reintroduced the Medicare for All Act in April with Rep. Debbie Dingell (D-Mich.) and Senate Health, Education, Labor, and Pensions Committee Ranking Member Bernie Sanders (I-Vt.). The senator said Friday that some of his top priorities in 2026 will be campaign finance reform, income and wealth inequality, the rapid deployment of artificial intelligence, and Medicare for All.
Earlier this month, another backer of that bill, US Sen. Chris Van Hollen (D-Md.), said: "We must stop tinkering around the edges of a broken healthcare system. Yes, let's extend the ACA tax credits to prevent a huge spike in healthcare costs for millions. Then, let's finally create a system that puts your health over corporate profits. We need Medicare for All."
It's not just progressives in Congress demanding that kind of transformation. According to Data for Progress polling results released late last month, 65% of likely US voters—including 78% of Democrats, 71% of Independents, and 49% of Republicans—either strongly or somewhat support "creating a national health insurance program, sometimes called 'Medicare for All.'"
The provision, part of the Senate budget bill, was described as "a blatant giveaway to the pharmaceutical industry that would keep drug prices high for patients while draining $5 billion in taxpayer dollars."
The deep-pocketed and powerful pharmaceutical industry notched a significant victory on Monday when the Senate parliamentarian ruled that a bill described by critics as a handout to drug corporations can be included in the Republican reconciliation package, which could become law as soon as this week.
The legislation, titled the Optimizing Research Progress Hope and New (ORPHAN) Cures Act, would exempt drugs that treat more than one rare disease from Medicare's drug-price negotiation program, allowing pharmaceutical companies to charge exorbitant prices for life-saving medications in a purported effort to encourage innovation. (Medications developed to treat rare diseases are known as "orphan drugs.")
The consumer advocacy group Public Citizen observed that if the legislation were already in effect, Medicare "would have been barred from negotiating lower prices for important treatments like cancer drugs Imbruvica, Calquence, and Pomalyst."
Among the bill's leading supporters is Sen. Martin Heinrich (D-N.M.), whose spokesperson announced the parliamentarian's decision to allow the measure in the reconciliation package after previously advising that it be excluded. Heinrich is listed as the legislation's only co-sponsor in the Senate, alongside lead sponsor Sen. John Barrasso (R-Wyo.).
"Sen. Heinrich should be ashamed of prioritizing drug corporation profits over lower medicine prices for seniors and people with disabilities," Steve Knievel, access to medicines advocate at Public Citizen, said in a statement Monday. "Patients and consumers breathed a sigh of relief when the Senate parliamentarian stripped the proposal from Republicans' Big Ugly Betrayal, so it comes as a gut punch to hear that Sen. Heinrich welcomed the reversal and continued to champion a proposal that will transfer billions from taxpayers to Big Pharma."
"People across the country are demanding lower drug prices and for Medicare drug price negotiations to be expanded, not restricted," Knievel added. "Sen. Heinrich should apologize to his constituents and start listening to them instead of drug corporation lobbyists."
The Biotechnology Innovation Organization, a lobbying group whose members include pharmaceutical companies, has publicly endorsed and promoted the legislation, urging lawmakers to pass it "as soon as possible."
"This is a blatant giveaway to the pharmaceutical industry that would keep drug prices high for patients."
The nonpartisan Congressional Budget Office has estimated that the ORPHAN Cures Act would cost U.S. taxpayers around $5 billion over the next decade.
Merith Basey, executive director of Patients For Affordable Drugs Now, said that "patients are infuriated to see the Senate cave to Big Pharma by reviving the ORPHAN Cures Act at the eleventh hour."
"This is a blatant giveaway to the pharmaceutical industry that would keep drug prices high for patients while draining $5 billion in taxpayer dollars," said Basey. "We call on lawmakers to remove this unnecessary provision immediately and stand with an overwhelming majority of Americans who want the Medicare Negotiation program to go further. Medicare negotiation will deliver huge savings for seniors and taxpayers; this bill would undermine that progress."