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On April Fool's Day, global and domestic health activists will demand that the pharmaceutical industry stop charging unethical prices for medications during a protest at the Pharmaceutical Research and Manufacturers of America (PhRMA). Activists will protest as a "PhRMA executive" operates a life-sized Uncle Sam puppet to defend PhRMA's prices. The activists will cut the puppet strings between the U.S. government (USG) and PhRMA, symbolically freeing our country to adopt pharmaceutical development strategies that serve the public interest and to oppose trade deals designed to line the pharmaceutical industry's pockets.
Activists will call on the U.S. government to pledge to reform drug development policies, support a global R&D agreement for more affordable medicines in the developing world, and oppose trade deals like the Trans-Pacific Partnership (TPP), which would extend drug company monopolies at the expense of patients' lives. "The U.S. Government can put a stop to the unethical practices that allow pharmaceutical companies to profit enormously on the backs of taxpayers and patients, pricing life-saving medications, already paid for via university research, out of reach," said Merith Basey, Executive Director of Universities Allied for Essential Medicines.
PhRMA is a lobbying organization representing most major American pharmaceutical companies, as well as a significant number of foreign corporations, and has worked to obscure recent scandals in drug pricing, arguing simply that pricing is complex. The biomedical research and development system that PhRMA defends has failed the sick, bankrupted public programs, and left millions of poor people to die worldwide.
The activists involved in Friday's protest are calling on the US. government and the pharmaceutical industry to adopt a patient-centered solution to this crisis. This solution must recognize that high drug prices disproportionately affect minorities, the poor, and the otherwise marginalized and vulnerable. "New drugs that cure Hepatitis C cost upwards of $84,000. Black men and women in the US account for 22% of Hepatitis C and die from the disease in middle age at twice the rate of whites. Systemic inequality means that Hepatitis C deaths continue to rise in the U.S. for many, despite the advent of highly effective interferon-free therapy. Hepatitis C now kills more Americans than HIV, but Gilead's price gouging bleeds public health programs dry, and brutally leaves patients without the medicine they need to survive," said Karyn Pomerantz from the Metro Washington Public Health Association.
With the support of the U.S. government, the pharmaceutical industry is pushing for longer-term monopolies in trade agreements like the TPP and the Transatlantic Trade and Investment Partnership (TTIP). These monopolies would delay the production and availability of lifesaving, affordable generic medicines. Despite this, the U.S. government has led the charge for the TPP and the TTIP, apparently blind to the inherent conflict of interest of allowing the pharmaceutical industry to help craft these trade agreements.
Novel and effective medications are here, or in the pipeline for cancer, heart disease, diabetes, clotting disorders, HIV and hepatitis C and yet they are not reaching those who need them most. "Patient lives are on the line now, we can't wait," said UAEM's Ali Greenberg. "We demand affordable prices and a stop to practices that block access to care, especially those promoted by the deadly terms included in the TPP." Ms. Greenberg continued, "We need the U.S. government to take the lead and to start proposing real solutions to the current global crisis in access to medicines."
Friday's action in front of PhRMA is part of a larger Global Day of Action against pharmaceutical industry greed, with actions taking place on April Fool's Day in Sydney, Rio de Janeiro, Tokyo, Delhi, Ahmedabad, New York City, Boston, San Francisco, and three other international cities that cannot yet be named due to the nature of the events. All of the actions will highlight scandals in drug development and price gouging that robs U.S. taxpayers, while leaving patients in developing countries without the medicine they need to survive. The USG must reject the provisions in the TPP that will negatively impact access to medicines, and support discussions around the creation and adoption of a global research and development agreement at the World Health Organization which would set standards for affordable pricing of medicines worldwide. As Jacob Levi from ACT UP put it, "It's time to stop letting the U.S. government play PhRMA's fool."
"Tupac said it decades ago, it continues to be true."
He may prefer Biggie over Tupac, but New York City Mayor Zohran Mamdani gave a nod to the latter's immortal observation on misplaced national priorities during an interview in which he condemned the US-Israeli war against Iran.
"I've made clear my very deep opposition to this war in Iran," Mamdani told Richard Gaisford in a "Talk to Al Jazeera" segment aired Thursday on the Qatari news network. "It is an opposition not just of a procedural nature or a political nature, but frankly of a moral nature."
"We are speaking about a war that has killed thousands of civilians, a war that is deeply unpopular across this city and across this country," Mamdani said. "Not just because of what we are seeing it result in, but also because it is utilizing tens of billions of dollars to kill people, money that could otherwise be spent on making life easier for people across this city and this country."
"The very things that I often speak about that are necessary for working class New Yorkers that we are told are impossible or unrealistic, they would cost a fraction of this tens of billions that we're seeing," the mayor asserted.
Gaisford asked Mamdani if he is frustrated that "$900 million a day [is] being spent on the war, when you have projects that cost much less that can make a difference."
"I think it should frustrate all of us, you know what I mean?" the democratic socialist mayor replied. "Tupac said it decades ago, it continues to be true, about the fact that we always seem to have money for war but not to feed the poor. And that is not the way politics should be; that is not what Americans want politics to be."
Mamdani was referring to Tupac Shakur's 1993 track "Keep Ya Head Up," which contains the lyrics, "You know, it's funny when it rains it pours/They got money for wars, but can't feed the poor."
Shakur's 1998 song "Changes" also feels relevant today, as the slain rapper asks, "Can't a brother get a little peace?/It's war on the streets and the war in the Middle East/Instead of war on poverty, they got a war on drugs so the police can bother me."
Watch Mamdani's interview with Gaisford here:
A 20-year-old suspect was found at the company's headquarters, where he was threatening to burn down the building.
A suspect was arrested in San Francisco Friday after being accused of throwing a Molotov cocktail at the home of Sam Altman, the CEO of the artificial intelligence firm OpenAI.
The 20-year-old man was found at the OpenAI headquarters about three miles away from Altman's home, where he was threatening to burn down the building, San Francisco police said.
The device the suspect threw onto Altman's property in the Russian Hill neighborhood caused a fire on the exterior gate. It was unclear whether Altman and his family were at home.
The suspect was in custody Friday, with charges pending.
Altman's company and other companies have been under fire as AI has expanded rapidly at President Donald Trump's urging, with the president issuing an executive order attacking states' ability to regulate the industry.
Experts have warned the expansion of generative AI threatens jobs and democracy, with political campaigns already using the technology to create fraudulent media in advertisements.
Massive, energy-sucking AI data centers have also been blamed for higher household electricity bills and water consumption.
Protesters have rallied against Altman's company for agreeing to provide its technology to the Department of Defense.
In November, The New York Times reported, a person who had once been associated with the anti-AI group Stop AI "expressed interest in causing physical harm to OpenAI employees," causing the company to lock down its headquarters.
On Friday, Stop AI condemned the attack on Altman's house and emphasized that the group "seeks to protect human life."
"We do not condone any violence whatsoever," said the group. "We pray everyone involved in this situation puts aside violence and finds peace, and we continue to hope the AI industry stops the development of frontier AI systems in the interest of public safety and the preservation of humanity. To the best of our knowledge, this incident did not involve anyone who has ever been associated with our group. And this action is wholly inconsistent with our values."
"While Americans worry about skyrocketing costs and another endless war, President Trump is focused on a taxpayer-funded vanity project," said Rep. Don Beyer.
On the same day that the US Bureau of Labor Statistics showed that inflation spiked at its fastest monthly rate in four years, the Trump administration unveiled renderings of President Donald Trump's proposed gold-covered 250-foot-tall arch to be built at Memorial Circle in Washington, DC.
The renderings, which were produced by architecture firm Harrison Design and posted on social media by the White House's rapid response account, show a gigantic arch that would be flanked on its corners by four gold lions and topped by a 60-foot-tall gold statue of what appears to be an angel.
🇺🇸 pic.twitter.com/zcH5TtaOu7
— Rapid Response 47 (@RapidResponse47) April 10, 2026
According to a Friday report in The Washington Post, some preservationists have expressed concerns that the arch, which would be more than twice the height of the Lincoln Monument, would disproportionately tower over the DC skyline, and would block views of Arlington National Cemetery.
Rep. Don Beyer (D-Va.) slammed the president for pushing construction of a gaudy gold-covered arch at a time when Americans are struggling due to the cost-of-living crisis worsened by his war in Iran.
"While Americans worry about skyrocketing costs and another endless war," he wrote in a social media post, "President Trump is focused on a taxpayer-funded vanity project that would choke traffic, block our skyline, and tower over sacred ground where those who served our nation are buried, including my own parents and sister."
Beyer added that the arch is "about Donald Trump's ego," and vowed, "we're going to stop it."
Rep. Katherine Clark (D-Mass.) responded to the renderings by reminding the White House that "Americans can't afford groceries."
Progressive activist Nina Turner had a similar reaction to Clark, posting that "people can’t afford rent" in response to the renderings.
Podcaster Brian Taylor Cohen contrasted the renderings of the arch with a statement Trump made earlier this month when he said "it’s not possible" for the federal government "to take care of daycare, Medicaid, Medicare, all these individual things," because it needs to fund wars instead.
University of Missouri English professor Karen Piper also remarked on the opportunity cost of building the arch, along with other assorted Trump projects.
"This is why they're going to take away your Social Security, saying we can't afford it," she wrote. "Ballrooms, arches, and Don Jr. draining the Treasury."
California Gov. Gavin Newsom, who has been named as a contender for the Democratic Party's 2028 presidential nomination, responded to the arch renderings by accusing Trump of "doing everything he can to wreck this country—this time with our nation's capital."
Rep. Jared Huffman (D-Calif.) took issue with the decision to inscribe the phrase "one nation under God" at the top of the arch.
"That phrase came from Cold War propaganda, not our Founders," observed Huffman. "Trump stamping it on his vanity arch tells you everything about what this project is: a Christian nationalist monument, paid for with your tax dollars."