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"At long last, the FDA is ending the regulatory paradox of Red 3 being illegal for use in lipstick, but perfectly legal to feed to children in the form of candy," said one advocate.
It's been used to color everything from candy to soft drinks to even watermelon—but after decades of knowing that it causes cancer, the U.S. Food and Drug Administration is finally banning erythrosine, popularly known as Red Dye No. 3, in foods and beverages.
Red Dye No. 3—commonly used to color maraschino cherries, fruit cocktails, toaster pastries, sodas, seasonal candies, cough syrups, and many other orally consumed products—has been known to cause cancer in animals since the 1980s. It has been banned in cosmetics since 1990. Manufacturers have until January 2027 to remove the toxic additive from products subject to the ban.
"This is exactly the action we need to see from the FDA."
"Because the FDA failed to uphold its legal obligation to fully ban cancer-causing additives, Red 3 remained permitted in foods, supplements, and oral drugs more than 34 years later," the Center for Science in the Public Interest said in a statement Wednesday. "That changed on January 16, 2025, thanks to a color additive petition filed by CSPI in 2022."
CSPI called the ban "a win for public health."
"At long last, the FDA is ending the regulatory paradox of Red 3 being illegal for use in lipstick, but perfectly legal to feed to children in the form of candy," Dr. Peter Lurie, president of the Center for Science in the Public Interest, said in a statement. "The primary purpose of food dyes is to make candy, drinks, and other processed foods more attractive. When the function is purely aesthetic, why accept any cancer risk?"
In addition to CSPI, numerous other groups and activists including the Center for Food Safety, Environmental Working Group (EWG), and Food & Water Watch (FWW) had petitioned the FDA for the ban.
"We wouldn't be celebrating this historic decision today without the relentless leadership of public health champions like Michael Jacobson and others who took up this fight decades ago on behalf of consumers," EWG president and co-founder Ken Cook said in a statement hailing the ban. "We all owe a debt of gratitude to Michael and the other early leaders who pushed the FDA to remove toxic chemical ingredients from the nation's food supply."
FWW senior food policy analyst Rebecca Wolf said that "this move by the FDA is long overdue, but represents a step in the right direction for consumer safety from harmful, cancer-causing chemicals."
"This is exactly the action we need to see from the FDA," Wolf added. "If the incoming FDA is serious about food safety and system reform, they should build on this win by endorsing scientifically sound policies and regulatory changes that Food & Water Watch has supported for years. These include ending the GRAS loophole that companies use to pollute our food system, removing antibiotics from animal feed, and supporting a ban on harmful chemicals in food."
"The Mexican government is both wise and on solid ground in refusing to allow its people to participate in the experiment that the U.S. government is seeking to impose."
Friends of the Earth U.S. on Monday released a brief backing Mexico's ban on genetically modified corn for human consumption, which the green group recently submitted to a dispute settlement panel charged with considering the U.S. government's challenge to the policy.
Mexican President Andrés Manuel López Obrador announced plans to phase out the herbicide glyphosate as well as genetically modified (GM) or genetically engineered (GE) corn in 2020. Last year he issued an updated decree making clear the ban does not apply to corn imports for livestock feed and industrial use. Still, the Biden administration objected and, after fruitless formal negotiations, requested the panel under the United States-Mexico-Canada Agreement (USMCA).
"The U.S. government has not presented an 'appropriate' risk assessment to the tribunal as called for in the USMCA dispute because such an assessment has never been done in the U.S. or anywhere in the world," said agricultural economist Charles Benbrook, who wrote the brief with Kendra Klein, director of science at Friends of the Earth U.S.
"The U.S. is, in effect, asking Mexico to trust the completeness and accuracy of the initial GE corn safety assessments carried out 15 to 30 years ago by the companies working to bring GE corn events to market."
The group's 13-page brief lays out health concerns related to GM corn and glyphosate, and the shortcomings of U.S. analyses and policies. It also stresses the stakes of the panel's decision, highlighting that "corn is the caloric backbone of the Mexican food supply, accounting, on average, for 50% of the calories and protein in the Mexican diet."
Blasting the Biden administration's case statement to the panel as "seriously deficient," Klein said Monday that "it lacks basic information about the toxins expressed in contemporary GMO corn varieties and their levels. The U.S. submission also ignores dozens of studies linking the insecticidal toxins and glyphosate residues found in GMO corn to adverse impacts on public health."
The brief explains that "since the commercial introduction of GE corn in 1996 and event-specific approvals in the 1990s and 2000s, dramatic changes have occurred in corn production systems. There has been an approximate fourfold increase in the number of toxins and pesticides applied on the average hectare of contemporary GE industrial corn compared to the early 1990s. Unfortunately, this upward trend is bound to continue, and may accelerate."
The U.S. statement's assurances about risks from Bacillus thuringiensis or vegetative insecticidal protein (Bt/VIP) residues "are not based on data and science," the brief warns.
"The U.S. is, in effect, asking Mexico to trust the completeness and accuracy of the initial GE corn safety assessments carried out 15 to 30 years ago by the companies working to bring GE corn events to market," the document says. "The Mexican government is both wise and on solid ground in refusing to allow its people to participate in the experiment that the U.S. government is seeking to impose on Mexico."
"The absence of any systematic monitoring of human exposure levels to Bt/VIP toxins and herbicides from consumption of corn-based foods is regrettable," the brief adds. "It is also unfortunate that the U.S. government rejected the Mexican proposal to jointly design and carry out a modern battery of studies able to overcome gaps in knowledge regarding GE corn impacts."
"The U.S. government's case against Mexico has no more scientific merit than its sham GMO regulatory regime, and should be rejected by the USMCA dispute resolution panel."
Friends of the Earth isn't the only U.S.-based group formally supporting the Mexican government in the USMCA process. The Center for Food Safety sent a 10-page submission by science director Bill Freese, an expert on biotech regulation, to the panel on March 15. His analysis addresses U.S. regulation of genetically modified organisms (GMO) along with the risks of GM corn and glyphosate.
"GMO regulation in the U.S. was crafted by Monsanto, now owned by Bayer, and is a critical part of our government's promotion of the biotechnology industry," Freese said last week, referring to the company known for the glyphosate-based weedkiller Roundup. "The aim is to quell concerns and promote acceptance of GMOs, domestically and abroad, rather than critically evaluate potential toxicity or allergenicity."
His submission notes that the U.S. Food and Drug Administration "does not require a GE plant developer to do anything prior to marketing its GE crop or food derived from it. Instead, FDA operates what it calls a voluntary consultation program that is designed to enhance consumer confidence and speed GE crops to market."
"When governmental review is optional; and even when it's conducted, starts and ends with the regulated company's safety assurance—what's the point?" Freese asked. "Clearly, it's the PR value of a governmental rubber stamp."
"The Mexican government's prohibition of GM corn for tortillas and other masa corn products is fully justified," he asserted. "The U.S. government's case against Mexico has no more scientific merit than its sham GMO regulatory regime, and should be rejected by the USMCA dispute resolution panel."
In a Common Dreams opinion piece last week, Ernesto Hernández-López, a law professor at Chapman University in California, pointed out that Mexico's recent submission to the panel also "offers scientific proof and lots of it," including "over 150 scientific studies, referred to in peer-review journals, systemic research reviews, and more."
"Mexico incorporates perspectives from toxicology, pediatrics, plant biology, hematology, epidemiology, public health, and data mining, to name a few," he wrote. "This clearly and loudly responds to American persistence. The practical result: American leaders cannot claim there is no science supporting the decree. They may disagree with or dislike the findings, but there is proof."
The Biden administration's effort to quash the Mexican policy notably comes despite the lack of impact on trade. While implementing its ban last year, "Mexico also made its largest corn purchase from the U.S., 15.3 million metric tons," National Geographicreported last month.
Kenneth Smith Ramos, former Mexican chief negotiator for the USMCA, told the outlet that "right now, it may not have a big economic impact because what Mexico is using to produce flour, cornmeal, and tortillas is a very small percentage of their overall imports; but that does not mean the U.S. is not concerned with this being the tip of the iceberg."
"The court today resoundingly reaffirmed what we have always maintained: The EPA's and Monsanto's claims of dicamba's safety were irresponsible and unlawful," said one plaintiff.
In what one plaintiff called "a sweeping victory for family farmers and dozens of endangered plants and animals," a federal court in Arizona on Tuesday rescinded the U.S. Environmental Protection Agency's 2020 approval of the highly volatile herbicide dicamba for use on certain genetically engineered crops.
In a 47-page ruling, U.S. District Judge David C. Bury found that the EPA failed to comply with public notice and comment requirements under the Federal Insecticide, Fungicide, and Rodenticide Act (FIFRA), legislation passed in 1947 to protect agricultural workers, consumers, and the environment.
"This is a vital victory for farmers and the environment," said George Kimbrell, legal director at the Center for Food Safety (CFS), a plaintiff in the case. "Time and time again, the evidence has shown that dicamba cannot be used without causing massive and unprecedented harm to farms as well as endangering plants and pollinators."
"The court today resoundingly reaffirmed what we have always maintained: The EPA's and Monsanto's claims of dicamba's safety were irresponsible and unlawful," Kimbrell added.
Dicamba has damaged millions of acres of U.S. cropland since the EPA, during the Trump administration, dubiously approved its use on genetically engineered cotton and soybeans developed by Monsanto, which was acquired by Bayer in 2018.
The EPA subsequently identified spray drift as the main environmental risk for dicamba due to its potential to contaminate nontargeted crops, declaring that since 2016 "there has been a substantial increase in the overall number of reported nontarget plant incidents."
As CFS explained on Tuesday:
In today's decision, the court canceled dicamba's over-the-top use, holding that EPA violated FIFRA's public input requirement prior to the approval. This violation is "very serious," according to the court, especially because the 9th Circuit previously held EPA failed to consider serious risks of over-the-top dicamba in issuing the prior registration. The court outlined the massive damage to stakeholders that were deprived of their opportunity to comment, such as growers that do not use over-the-top dicamba and suffered significant financial losses and states that repeatedly reported landscape-level damage yet, in the same 2020 decision, lost the ability to impose restrictions greater than those imposed by the federal government without formal legislative and/or rulemaking processes. As a result, the court found "the EPA is unlikely to issue the same registrations" again after taking these stakeholders' concerns into account.
"We are grateful that the court held the EPA and Monsanto accountable for the massive damage from dicamba to farmers, farmworkers, and the environment, and halted its use," Lisa Griffith of the National Family Farm Coalition—another plaintiff in the case—said in a statement Tuesday. "The pesticide system that Monsanto sells should not be sprayed as it cannot be sprayed safely."
Tuesday's decision in Arizona follows a July 2022 ruling by the 8th U.S. Circuit Court of Appeals in St. Louis that found Monsanto and BASF were liable for damage to a Missouri peach farmer's groves caused by dicamba.
A 2021 EPA report revealed that high-ranking Trump administration officials intentionally excluded scientific evidence of dicamba-related hazards, including the risk of widespread drift damage, before reapproving the dangerous chemical. A separate EPA report described the widespread harm to farmers and the environment caused by dicamba during the 2020 growing season.
"Every summer since the approval of dicamba, our farm has suffered significant damage to a wide range of vegetable crops," said Rob Faux, a farmer and communications manager at the advocacy group Pesticide Action Network, a case plaintiff. "Today's decision provides much-needed and overdue protection for farmers and the environment."