As lawsuits mount against the pharmaceutical company Purdue Pharma over its knowledge that one of its best-selling drugs was addictive and dangerous, a newly- uncovered Justice Department report shows that the multi-billion dollar corporation also knew that patients were abusing OxyContin shortly after the drug's release.
The role of Purdue owners and executives in promoting oxycontin is becoming clearer over time. This is a dark and disturbing story by @BarryMeier of how profit motives in the pharmaceutical industry can corrupt. #opioidepidemic #opioidcrisis https://t.co/bDmoVqJ38d
— Ira Wilson (@ibwilson_health) May 29, 2018
— Patrick Radden Keefe (@praddenkeefe) May 29, 2018
Almost immediately after releasing OxyContin in 1996, Purdue Pharma received reports that patients were crushing and snorting the drug and stealing it from pharmacies, and that some doctors were beginning to sell prescriptions for the highly addictive painkiller, which is chemically similar to heroin.
According to the New York Times' report on the DOJ document, Purdue's general counsel wrote in early 1999, "We have in fact picked up references to abuse of our opioid products on the internet."
That same year, an OxyContin sales representative wrote in an email, "I feel like we have a credibility problem with our product," after a doctor in Florida was arrested for illegally prescribing the drug. Sales representatives were discouraged by Purdue from raising concerns about abuse, with one saying his manager told him that "his job was to sell drugs, not to determine if a 'doctor was a drug pusher.'"
Purdue has claimed it did not learn of growing opioid abuse until 2000, when it was alerted by a U.S. attorney in Maine.
But by June 2000, the company's vice president of marketing wrote that he had long been receiving news of OxyContin abuse "all the time and from everywhere."
"Some pharmacies would not even stock MS Contin for fear they would be robbed," wrote the vice president. "In Wisconsin, Minnesota, and Oklahoma, we had physicians indicted for prescribing too much MS Contin."
The formerly confidential DOJ report came out of the same four-year investigation that led prosecutors to push for the indictments of three Purdue officials on felony fraud charges, when they discovered that the company was aggressively marketing OxyContin as safe for long-term use even though it knew the drug was addictive.
The George W. Bush administration opted to settle the case instead, with the executives and the company paying $634.5 million in fines in 2007.
Since then, Purdue Pharma has been sued by more than a dozen states for its deceptive marketing practices, while overdose deaths from OxyContin and other opioids have continued to rise steadily.