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The agency demanded that all parties protect civilians and reiterated the secretary-general's call "to end the fighting and engage in diplomatic negotiations."
Since the United States and Israel launched an unprovoked war on Iran at the end of February, more than 1,100 youth have been killed or injured in related violence across the Middle East, the United Nations Children's Fund said Wednesday, calling for a swift diplomatic resolution.
"The situation is becoming catastrophic for millions of children across the region," UNICEF said in a statement, noting that at least 200 children are reportedly dead in Iran, 91 in Lebanon, four in Israel, and one in Kuwait. "These numbers will likely climb as the violence intensifies and spreads."
Most of the kids killed in Iran died in what mounting evidence suggests was a US attack on the Shajareh Tayyebeh girls' school in Minab on February 28. That attack killed an estimated 175 people, mostly students ages 7-12, part of an overall death toll that the Iranian government has said exceeds 1,300.
Responding to the school bombing, Gordon Brown, a former UK prime minister who's now the UN special envoy for global education, argued in a Guardian opinion piece Thursday that "the world will now need stronger mechanisms to ensure accountability," such as a body complementing the International Criminal Court but specifically for children, "focusing its attention on the bombing of schools, abductions of pupils, and militias that enslave boys and girls."
With the widening conflict in the Middle East, UNICEF noted Wednesday, "widespread disruption to education has left millions of children out of school across the region, while hundreds of thousands of children have been displaced by unrelenting bombardment."
In Lebanon, where Israeli attacks are allegedly targeting the Lebanese political and paramilitary group Hezbollah despite a November 2024 ceasefire deal, nearly 800,000 people, including around 200,000 children, have been forced from their homes, according to Mercy Corps. The Lebanese government has said at least 570 people have been killed and 1,444 injured.
"Civilian infrastructure, including hospitals, schools, and water and sanitation systems—upon which children depend to survive—have been attacked, damaged, or destroyed by parties to the conflict," UNICEF said. "Nothing justifies the killing and maiming of children, or the destruction and disruption of essential services that children depend on."
"Grave violations against children in armed conflict can constitute violations of international law, including international humanitarian law, and international human rights law," the UN agency continued.
Across Iran, several United Nations Educational, Scientific, and Cultural Organization (UNESCO) World Heritage sites have also been damaged by the US-Israeli war, which experts worldwide argue violates both the US Constitution and UN Charter.
The UN Security Council, which is currently led by President Donald Trump's administration, on Wednesday adopted a resolution condemning Iran's retaliatory attacks on Bahrain, Kuwait, Oman, Qatar, Saudi Arabia, the United Arab Emirates, and Jordan—nations that host US military bases—without even mentioning the US-Israeli bombing campaign.
UN Secretary-General António Guterres last Friday demanded a return to negotiations. Trump, who abandoned a previous Iranian nuclear deal during his first term, ditched recent talks with Iran in favor of bombing the country with Israeli Prime Minister Benjamin Netanyahu—who has used war on Iran to again close crossings into the Gaza Strip, or as critics have put it, reinstate a "starvation policy" in the Palestinian territory devastated by Israel's 29-month genocidal assault.
In addition to reiterating "the secretary-general's call on parties to the conflict to end the fighting and engage in diplomatic negotiations," UNICEF on Wednesday urged everyone involved "to take all necessary precautions in the choice of means and methods of warfare to minimize harm to civilians, including by avoiding the use of explosive weapons that disproportionally affect children."
"The region's children—all 200 million of them—are counting on the world to act quickly," the agency concluded.
A Wednesday letter signed by every member of the US Senate Democratic Caucus but Sen. John Fetterman (D-Pa.)—who previously helped Republicans block a war powers resolution intended to halt Trump's assault on Iran—called for a probe of the Minab school attack and sounded the alarm about Defense Secretary Pete Hegseth's rhetoric that "only serves to endanger civilians."
Specifically, Hegseth has said that the US assault on Iran, which they're calling Operation Epic Fury, would have "no stupid rules of engagement," and there will be "death and destruction from the sky all day long."
“This is during an agreed ceasefire," a UNICEF spokesperson said. "The pattern is staggering."
Eight children have been killed by Israeli attacks in Gaza over the past two days. They are among 67 children who have been killed since last month's agreement for a "ceasefire" in Gaza was signed, according to a new report from the United Nations Children's Fund.
“Yesterday morning, a baby girl was reportedly killed in Khan Younis by an airstrike, while the day before, seven children were killed in Gaza City and the south,” said UNICEF spokesperson Ricardo Pires on Friday.
The seven children were among dozens of Palestinians who were killed or injured by an Israeli quadcopter attack in Gaza City on Wednesday, according to Doctors Without Borders, also known as Médecins Sans Frontières (MSF).
“At around 11:00 am, we heard gunfire from quadcopters,” said Zaher, an MSF nurse working at a mobile clinic in Gaza City. “Shortly after, we received two casualties. The first was a woman with a leg injury. A little later, a 9-year-old girl arrived with an injury on her face caused by gunfire from the quadcopters.”
Last month, Israel signed an agreement with Hamas that required both parties to cease hostilities with one another. But since the deal went into effect on October 11, Israel has carried out attacks in Gaza on 35 of the last 42 days.
The Gaza Media Office alleges that Israel has committed nearly 400 ceasefire violations in just over a month—which have included airstrikes, shellings, and direct shootings of civilians, as well as frequent incursions by Israel past the agreed-upon yellow withdrawal lines. At least 312 Palestinians have been killed and 760 injured.
“This is during an agreed ceasefire," Pires emphasized to reporters. "The pattern is staggering,”
Shortly after Pires' announcement, Israel launched a new ground invasion across the yellow line on Friday afternoon, which has reportedly left another displaced person dead near Khan Younis and thousands more people in North Gaza neighborhoods fleeing for their lives.
After two years of genocidal warfare, over 20,000 Palestinian children are confirmed to have been killed, while another 3,000 to 4,000 have lost either one or both of their limbs.
“As we have repeated many times, these are not statistics: Each was a child with a family, a dream, a life–suddenly cut short by continued violence," Pires said.
Gaza's health infrastructure lies in disrepair following two years of relentless bombing, which left nearly all of its hospitals and clinics either partially or fully destroyed.
As another stipulation of the ceasefire deal, Israel was required to lift its blockade on humanitarian aid entering the strip, which had left the people of Gaza on the brink of starvation and unable to perform basic medical care.
But in retaliation for what Israel alleged was a failure by Hamas to return the remains of some hostages abducted by Hamas militants on October 7, 2023, Israel cut off the largest port of entry for humanitarian aid, the Rafah Crossing, which remains closed.
After several weeks in which aid was nearly all choked off, the number of trucks entering the strip has increased in recent days. But according to the World Food Program (WFP), hundreds of thousands of people still remain in dire need of food assistance, and the amount currently entering the strip is far too little.
Only about 30% of WFP's target food parcels have been allowed to be distributed, though it says that it has been able to move that number upward more quickly in recent days.
Abeer Etefa, a spokesperson for the WFP, said that while this is “a step in the right direction... a lot of these food supplies stay in border crossing points for long days and therefore you know the possibility of them going bad is high.”
Pires said that as winter approaches, hundreds of thousands of children are “sleeping in the open” and “trembling in fear while living in flooded, makeshift shelters."
“For hundreds of thousands of children living in tents over the rubble of their former homes, the new [winter] season is a threat multiplier," he said. "Children are shivering through the night with no heating, no insulation, and too few blankets.”
As Gaza's medical system lies in ruin, UNICEF says over 4,000 children urgently need to be evacuated from the strip. But even after the ceasefire deal, Palestinian journalist Eman Abu Zayed reports in Truthout that securing medical referrals from the Israeli government and traveling for treatment outside the strip is a "near-impossible task."
“Gaza's doctors tell us of children they know how to save but cannot,” said Pires. He said they were children "with severe burns, shrapnel wounds, spinal injuries, traumatic brain injuries, and children with cancer who have lost months of treatment. Premature babies who need intensive care. Children who need surgeries that simply cannot be done inside Gaza today.”
“Every child killed is an irreplaceable loss. For the sake of all children in Gaza, this war must end now.”
After two years of US-backed Israeli genocide in Gaza that's left hundreds of thousands of Palestinian children dead, maimed, starved, sickened, and displaced and countless others traumatized for life, a key United Nations leader on Wednesday urged an immediate ceasefire and entry of humanitarian aid into the embattled strip.
“In the last two years, a staggering 64,000 children have reportedly been killed or maimed across the Gaza Strip, including at least 1,000 babies," United Nations Children's Fund (UNICEF) Executive Director Catherine Russell said Wednesday. "We don’t know how many more have died due to preventable illnesses or are buried under the rubble."
Russell's remarks came days after UNICEF spokesperson James Elder also urged an end to what he called a "war on children."
The charity Save the Children and others say at least 20,000 children are among the more than 67,000 Palestinians killed by Israeli forces in Gaza over the past two years. That's one child every hour in what the UN agency for Palestinian refugees last year reported was a higher child death toll than in the previous four years of all the world's armed conflicts combined.
Israeli forces have killed at least 20,000 children in Gaza since October 2023. This is a deeply shameful statistic for our collective humanity – a horrific new low.Every single one of these 20,000 children had names, favourite subjects in school, and hopes and dreams for the future.
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— Save the Children UK (@savechildrenuk.bsky.social) September 8, 2025 at 7:00 AM
Using Gaza Health Ministry data—which have been deemed generally accurate by experts including Israeli intelligence officials—Western media outlets including The Washington Post and The Guardian have published lists of more than 18,000 Palestinian children killed in Gaza since October 2023.
Experts, including the authors of multiple peer-reviewed studies in the prestigious British medical journal The Lancet, say the actual death toll is much higher, and will likely not be known for some time, as thousands of missing people are presumed dead and buried beneath the rubble of bombed buildings in a territory in which 90% of all homes have been destroyed.
According to the United Nations Office of the High Commissioner for Human Rights, nearly 7 in 10 Palestinians killed in Gaza between November 2023 and April 2024 were women and children. As Israeli officials continued to push specious claims of a historically low civilian-to-combatant kill ratio in Gaza, leaked classified Israel Defense Forces intelligence files revealed that 5 in 6 Palestinians—83%—killed by the IDF through the first 19 months of the war were, in fact, civilians.
While Israel claims it is waging its war with unparalleled effort to avoid harming civilians, facts on the ground paint a very different—and very bloody—picture. According to many Palestinian and international doctors and nurses who worked in Gaza, Israeli forces deliberately shot children with intent to kill, often aiming at their heads and chests. IDF troops have repeatedly admitted to being ordered to fire live bullets and artillery shells into crowds of starving aid-seeking civilians, including children.
Israeli troops have also admitted to being ordered to shoot to kill “anyone who enters” a so-called “kill zone” in central Gaza, including children. One IDF soldier even boasted online about how “fun” it is to kill Palestinian children, while another said in a video uploaded to social media that “we are looking for babies, but there are no babies left"—so instead he "killed a girl that was 12."

Following the Hamas-led October 7, 2023 attack on Israel, IDF commanders dramatically loosened rules of engagement, effectively allowing an unlimited number of civilians to be killed when targeting a single Hamas member, no matter how low-ranking. Combined with the use of artificial intelligence to rapidly select targets and the use of US-supplied 1,000- and 2,000-pound bombs that can level entire city blocks, wholesale massacres of dozens or more Palestinians ensued.
Last year, UN Secretary-General António Guterres for the first time added Israel to his so-called “List of Shame” of countries that kill and injure children during wars and other armed conflicts.
A handful of Gaza's child victims are known the world over, like Hind Rajab, the 5-year-old girl who was seriously wounded in January 2024 Israeli tank attack on her family's Kia hatchback but survived, surrounded by half a dozen slain relatives and under heavy fire, before being killed along with the paramedics sent to save her. Some Israelis and their US supporters denied that Hind Rajab ever existed, part of a wider pattern of denial—a recurring theme throughout history's genocides.
But largely due to the sheer scale of slaughter, most of the children killed by Israeli bombs, bullets, and blockade will remain nameless statistics to the world, despite the best efforts of Gaza officials and international activists to record and remember them. In September 2024, for example, the Gaza Health Ministry published a 649-page database of Palestinians killed by Israel. The first 14 pages of the document were filled with the names of babies. Last May, it took 24 hours for participants at a Harvard University vigil to read aloud the names of nearly 12,000 children killed in Gaza.
Here is a list of the names we know from the more than 11,500 Palestinian children killed during Israel’s continuing war on Gaza ⤵️
Know their names: https://t.co/l9T4EJlRKT pic.twitter.com/vaLsXK7r6P
— Al Jazeera English (@AJEnglish) February 2, 2024
Some—like a 9-year-old girl who was pulled from the rubble of her family home in Khan Younis after a December 2023 Israeli airstrike that killed her father and her only brother—have even argued that people killed quickly by Israeli bombs and bullets were the "lucky" ones, as many survivors faced unspeakable physical and psychological trauma. Thousands of children have had one or more limbs amputated, often without anesthesia, due to the systematic obliteration of Gaza's healthcare infrastructure and a "complete siege" for which former Israeli Defense Minister Yoav Gallant is wanted by the International Criminal Court (ICC).
Israel is using the siege as a weapon to deliberately starve Palestinians in Gaza, with children often the worst affected by a famine that's killed at least 470 people and likely many more, while starving hundreds of thousands of others. Like Gallant, Israeli Prime Minister Benjamin Netanyahu is also a fugitive from the ICC, wanted for alleged crimes against humanity and war crimes including murder and forced starvation.
"Famine persists in Gaza City and is spreading to the south, where children are already living in dire conditions," UNICEF's Russell said Wednesday. "The crisis of malnutrition, especially among infants, remains shocking. Months without adequate food have caused lasting harm to children’s growth and development."

Thousands of Palestinian children have also lost one or both parents to Israeli attacks. Some have seen their entire families wiped out in airstrikes. A new acronym has even been coined to describe some of these orphans: WCNSF, or “wounded child, no surviving family.”
All this killing, maiming, starving, orphaning, and forced displacement of hundreds of thousands of Palestinian minors has wrought what one mother there called the "complete psychological destruction" of Gaza's children. A December 2024 study found that nearly all children in Gaza believed their deaths were imminent—and nearly half of them wanted to die.
To end the physical and psychic suffering of Gaza's children, Russell and others are imploring Israel to end the war—a prospect that now seems closer than ever to being realized amid reportedly fruitful ceasefire talks.
“UNICEF welcomes all efforts to end the war and chart a path towards peace in Gaza and the region," Russell said. "Any plan must lead to a ceasefire, the release of hostages, and the safe, rapid, and unimpeded passage of humanitarian relief—through all available crossings and routes—at the scale desperately needed by all Gazans, especially children."
“Every child killed is an irreplaceable loss," Russell added. "For the sake of all children in Gaza, this war must end now.”