April, 01 2009, 02:01pm EDT
Drug-Induced Dementia and Delirium Common in Seniors But Often Undetected, Public Citizen Says
Condition Is Usually Reversible, Can Be Caused by 136 Drugs Listed on WorstPills.org
WASHINGTON
Older patients become more susceptible to drug-induced dementia and
delirium as they age, but the symptoms are often overlooked by doctors
who don't realize that the condition may be caused by drugs and
reversed, Public Citizen writes in a Worst Pills, Best Pills News article released today on WorstPills.org, the organization's drug safety Web site.
Unlike most forms of dementia, such as Alzheimer's disease, which
cannot be reversed, dementia caused by prescription drug use may be
stopped by discontinuing the offending medication. The drug safety
experts at Public Citizen have identified 136 commonly prescribed
medications, especially certain antidepressants and pain medications,
that can cause difficulty thinking.
Drug-induced dementia and delirium are commonly misattributed to
underlying medical illness or merely to "old age." But by stopping or
modifying the dosage of numerous, frequently prescribed drugs, most
patients can be restored to a pre-drug state of mental clarity.
Older people are more susceptible to drug-induced delirium and
dementia because the body's ability to rid itself of drugs decreases
with age, often because of normal age-related decrease in kidney and
liver function. Also, older patients are often prescribed multiple
drugs at the same time, resulting in complicated interactions and
enhanced side effects. Some research also suggests older patients'
brains may be more sensitive to drugs' effects on the central nervous
system.
"Sadly, doctors don't always recognize cognitive impairment as a
side effect, so many patients needlessly suffer from this debilitating
but reversible condition," said Sidney Wolfe, M.D., director of Public
Citizen's Health Research Group and acting Public Citizen president.
"After beginning new drugs, doctors, patients and their families should
watch for subtle changes in cognition and assume changes may be caused
by drug therapy. People already suffering from some cognitive
impairment are most susceptible."
Delirium is a syndrome of changes in vision, hearing and thinking
that usually starts abruptly and is commonly seen in the hospital
setting or during an acute illness; symptoms typically improve when the
cause is treated. Dementia, on the other hand, is a chronic alteration
in thinking that progresses slowly. Alzheimer's disease is dementia's
most common cause, but it also can be caused by strokes and other
conditions.
WorstPills.org includes the
full list of 136 implicated drugs. Some examples include: widely used
antihistamines such as diphenhydramine (Benedryl); a drug widely used
for treating urinary incontinence, tolteridine (Detrol); a nausea
treatment drug, metoclopramide (Reglan); and drugs in the
benzodiazepine category such as popular sleeping pills Ambien
(zolpidem) and Lunesta (eszopiclone).
Worst Pills, Best Pills News is a monthly newsletter available in print and electronic formats through Public Citizen's subscription Web site, . The article about drug-induced dementia and delirium will be available free for the next seven days. The site has other searchable information about the uses, risks and side effects associated with prescription medications.
WorstPills.org is an
unbiased analysis of information from a variety of sources, including
well-regarded medical journals and unpublished data obtained from the
Food and Drug Administration, that allows Public Citizen to sound the
alarm about potentially dangerous drugs long before they are banned by
the federal government and to recommend safer drugs. For example,
Public Citizen warned consumers about the dangers of Vioxx, ephedra,
Baycol and Propulsid years before they were pulled from the market.
Public Citizen is a nonprofit consumer advocacy organization that champions the public interest in the halls of power. We defend democracy, resist corporate power and work to ensure that government works for the people - not for big corporations. Founded in 1971, we now have 500,000 members and supporters throughout the country.
(202) 588-1000LATEST NEWS
'The Opposite of Leadership': US Vetoes Palestine's UN Membership
Palestine's permanent observer at the United Nations said the resolution's failure "will not break our will, and it will not defeat our determination."
Apr 18, 2024
U.S. President Joe Biden's administration on Thursday used the country's veto power at the United Nations Security Council to block Palestine's bid to become a full member of the U.N.
While 12 nations voted in favor of Palestinian membership and two abstained, the United States is one of five countries—along with China, France, Russia, and the United Kingdom—who have veto authority at the Security Council.
Since Israel launched what the International Court of Justice has said is a "plausibly" genocidal assault of the Gaza Strip in response to a Hamas-led October attack, the Biden administration has blocked three cease-fire resolutions at the Security Council. Under mounting global pressure, the U.S. finally abstained last month, allowing a cease-fire measure to pass.
In the lead-up to Thursday's vote, the Biden administration was pressuring other countries to oppose the Palestinian Authority's renewed membership effort so it could possibly avoid a veto, according to leaked cables obtained by The Intercept.
"Take a moment to ponder how isolated Biden has made the U.S.," said Trita Parsi, executive vice president of the Quincy Institute for Responsible Statecraft, after the veto. "Biden lobbied Japan, South Korea, and Ecuador HARD to oppose the Palestine resolution so that the U.S. wouldn't have to veto. They refused. So Biden cast his fourth veto in seven months (!!) This is the opposite of leadership."
In addition to the nations Parsi highlighted, Algeria, China, France, Guyana, Malta, Mozambique, Russia, Sierra Leone, and Slovenia voted for giving Palestine full U.N. membership while Switzerland and the United Kingdom abstained.
After the vote, U.N. Newsreported on remarks from Riyad Mansour, a U.N. permanent observer for the state of Palestine:
"We came to the Security Council today as an important historic moment, regionally and internationally, so that we could salvage what can be saved. We place you before a historic responsibility to establish the foundations of a just and comprehensive peace in our region."
Council members were given the opportunity "to revive the hope that has been lost among our people" and to translate their commitment towards a two-state solution into firm action "that cannot be maneuvered or retracted," and the majority of council members "have risen to the level of this historic moment, and they have stood on the side of justice and freedom and hope, in line with the ethical and humanitarian and legal principles that must govern our world and in line with simple logic."
"The fact that this resolution did not pass will not break our will, and it will not defeat our determination," Mansour added. "We will not stop in our effort. The state of Palestine is inevitable. It is real. Perhaps they see it as far away, but we see it as near, and we are the faithful."
Parsi said that "a Western-friendly senior Global South diplomat" told him of Biden's veto: "Whatever agonizing claim the U.S. had to lead a self-appointed free world has died a very loud public death on the Security Council horseshoe tonight. YOU CAN'T LEAD IF YOU CAN'T LISTEN."
Biden, a Democrat seeking reelection in November, has faced fierce criticism in the United States and around the world for U.S. complicity in Israel's war on Gaza—which Hamas, not the Palestinian Authority, has controlled for nearly two decades. In under seven months, Israeli forces have killed 33,970 Palestinians, injured another 76,770, displaced most of the besieged enclave's 2.3 million population, devastated civilian infrastructure, and severely limited the flow of lifesaving humanitarian assistance.
Israel—which already got $3.8 billion in annual U.S. military aid before October 7—continues to receive weapons support from the Biden administration, even as a growing chorus of critics, including some Democrats in Congress, argues that the arms transfers violate U.S. and international law.
Keep ReadingShow Less
'Shameful': Columbia Greenlights Police Crackdown on Anti-War Encampment
Even after dozens of students were arrested, hundreds "rushed to take the place of their classmates" and continued the protest.
Apr 18, 2024
The arrests of dozens of Columbia University and Barnard College students on Thursday "galvanized" other supporters of Palestinian rights on the campuses, as hundreds of students occupied the school's western lawn after New York City police filled at least two buses with protesters who had been detained for setting up an encampment.
"Disclose, divest, we will not stop, we will not rest," chanted hundreds of students as they marched around the area where organizers had set up a tent encampment early Wednesday morning.
Columbia President Minouche Shafik informed the campus community on Thursday that she had authorized the police to clear the encampment.
As it has been in the past, the school has become a center of anti-war protests—and crackdowns by school officials and the police—since Israel began its bombardment of Gaza in October.
Pro-Palestinian students and alumni have demanded that Columbia divest from companies that profit from Israel's apartheid policies in the occupied Palestinian territories and cancel its dual degree program with Tel Aviv University.
In response to pro-Palestinian demonstrations, Columbia in November suspended the campus chapters of Jewish Voice for Peace and Students for Justice in Palestine—an action that pushed the New York Civil Liberties Union and Palestine Legal to file a lawsuit on behalf of the students last month.
On Thursday, police and Columbia employees took down about 50 tents that had been up for more than a day and disposed of them in trash cans and alleyways—but The New York Times reported later that "demonstrators repitched a couple of tents, and ... recovered the main signage from the encampment as well," while hundreds of students were "still gathered and chanting on the south side of the grass."
The arrests came a day after Shafik testified before the U.S. House Committee on Education and the Workforce about antisemitism on campus.
U.S. Rep. Ilhan Omar (D-Minn.), whose daughter, Isra Hirsi, was among the Barnard students who were suspended on Thursday for participating in the encampment protest, questioned Shafik about whether antisemitic protests have actually taken place at Columbia, prompting the president to say there have not.
"There has been a rise in targeting and harassment against anti-war protesters, because it's been pro-war and anti-war protesters is what it seems, like, correct?" asked Omar.
"Correct," replied Shafik.
On Thursday, Omar posted on social media two images of protesters at Columbia: one from the encampment this week, and one from 1968, when students protested the U.S. war in Vietnam.
New York City Council member Tiffany Cabán was among those who condemned the university's crackdown on the protests on Thursday.
"Suspending and arresting Columbia/Barnard student activists and disbanding student organizations—including Jewish students and organizations—doesn't combat antisemitism or increase safety," said Cabán. "All it does is punish and intimidate those who believe in human rights for Palestinians. Shameful."
Keep ReadingShow Less
'The Pressure Is Working': Biden Weighs Climate Emergency Declaration
Campaigners urged the president to "keep listening to the millions of young, people of color, and working-class voters who are demanding climate policy that meets the moment."
Apr 18, 2024
The youth-led Sunrise Movement on Thursday celebrated Bloombergreporting that "White House officials have renewed discussions about potentially declaring a national climate emergency."
The Wednesday revelation came just two days after six young activists were arrested outside Vice President Kamala Harris' Los Angeles, California home to increase pressure on the Biden administration to make such a declaration, which would unlock various federal powers to combat the fossil fuel-driven global crisis.
According to Bloomberg:
Top advisers to President Joe Biden have recently resumed talks about the merits of such a move, which could be used to curtail crude exports, suspend offshore drilling, and curb greenhouse gas emissions, according to people familiar with the matter who asked not to be named because a final decision has not been made.
White House advisers are divided over the idea of declaring a climate emergency, with some saying it wouldn't provide Biden with enough newfound authority to make substantial changes, the people said. Others, however, argue such an announcement would galvanize climate-minded voters.
"The pressure is working. Let's keep it up," Sunrise said on social media, highlighting some of what Biden—who claimed last year that "practically speaking," he had already declared a national climate emergency—could do with a real declaration.
Sunrise wasn't alone in welcoming the news. The Center for Popular Democracy (CPD) Action said that "we've BEEN calling for a climate emergency!! Now, the White House is considering declaring one."
The group urged Biden to "keep listening to the millions of young, people of color, and working-class voters who are demanding climate policy that meets the moment."
As Biden and Harris have campaigned for reelection in November—when they are expected to face former Republican President Donald Trump, whose plan for the planet is "drill, baby, drill"—the Democrats have encountered intense pressure from campaigners including members of CPD and Sunrise to step up their climate actions.
"I'm on the frontlines raising my voice for my Black and Latine families and friends, because I know that we deserve to have affordable housing and healthcare, we deserve an administration who will fight for us, but instead of declaring a climate emergency, we are seeing Biden and Harris expand oil and gas production to record levels," 18-year-old Ariela Lara, who was arrested at Harris' house, said Monday.
Climate campaigners have praised the Biden administration for parts of the Inflation Reduction Act and a recent pause on liquefied natural gas exports but blasted the president for skipping last year's United Nations summit, continuing fossil fuel lease sales, and enabling the Mountain Valley Pipeline, Willow oil project, and construction of the nation's largest offshore oil terminal.
Keep ReadingShow Less
Most Popular